Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 2/20 | 0.46 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | SCN7A | Q01118 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 3/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.34 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | ACACA | Q13085 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3719879 | 0.83 | ACACB (0.42) | ACACBACACAP2RX3P2RX2 | |
| SCHEMBL3720071 | 0.83 | PDE4B (0.49) | PDE4BSMN1; SMN2SCN7AKCNH2SCN9A | |
| SCHEMBL3719881 | 0.82 | MTNR1A (0.46) | SMN1; SMN2SCN9AACACBMAPT | |
| SCHEMBL3717034 | 0.82 | SCN7A (0.49) | PDE4BSMN1; SMN2SCN7AKCNH2PPARG | |
| SCHEMBL3720433 | 0.82 | SCN7A (0.49) | PDE4BSMN1; SMN2SCN7AKCNH2PPARG | |
| SCHEMBL3720069 | 0.82 | CHRM5 (0.34) | SCN7AKCNH2PPARGSCN5ASCN2A | |
| SCHEMBL3727930 | 0.81 | SCN9A (0.34) | SCN7AKCNH2SCN9AACACBACACA | |
| SCHEMBL3721868 | 0.80 | PDE4B (0.48) | PDE4BSCN7AKCNH2SCN9AMAPT | |
| SCHEMBL3720755 | 0.80 | PDE4B (0.46) | PDE4BSMN1; SMN2PPARGMAPTALDH1A1 | |
| SCHEMBL3719589 | 0.80 | MAPT (0.34) | SCN7AKCNH2SCN9ASCN5ASCN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |