Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | XBP1 | P17861 | 1/20 | 0.50 |
| ▸ | MPI | P34949 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10095184 | 0.71 | MAPT (0.74) | IGF1RMAPTKMT2AMEN1KDM4E | |
| SCHEMBL16111649 | 0.71 | KMT2A (0.50) | IGF1RMAPTKMT2AMEN1KDM4E | |
| SCHEMBL3720353 | 0.71 | IGF1R (0.51) | IGF1RMAPTKMT2AMEN1KDM4E | |
| SCHEMBL3720355 | 0.71 | IGF1R (0.51) | IGF1RMAPTKMT2AMEN1KDM4E | |
| SCHEMBL12475443 | 0.70 | GSK3B (0.75) | IGF1RMAPTKMT2AMEN1KDM4E | |
| SCHEMBL9252177 | 0.70 | GSK3B (0.75) | IGF1RMAPTKMT2AMEN1KDM4E | |
| SCHEMBL9252170 | 0.70 | GSK3B (0.75) | IGF1RMAPTKMT2AMEN1KDM4E | |
| SCHEMBL15421922 | 0.69 | DHFR (0.61) | IGF1RMAPTKMT2AMEN1KDM4E | |
| SCHEMBL9352855 | 0.68 | IGF1R (0.51) | IGF1RMAPTKMT2AMEN1KDM4E | |
| SCHEMBL1249176 | 0.68 | IGF1R (1.00) | IGF1RMAPTKMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11629131-B2 | Coupled recognition/detection system for in vivo and in vitro use | CORNELL UNIVERSITY (US) | 2023-04-18 | — | — | US | disclosed |
| US-20190185434-A1 | COUPLED RECOGNITION/DETECTION SYSTEM FOR IN VIVO AND IN VITRO USE | UNIV CORNELL (US) | 2019-06-20 | — | — | US | disclosed |
| US-10316000-B2 | Coupled recognition/detection system for in vivo and in vitro use | CORNELL UNIVERSITY (US) | 2019-06-11 | — | — | US | disclosed |
| EP-2398775-B1 | COUPLED RECOGNITION/DETECTION SYSTEM FOR IN VIVO AND IN VITRO USE | UNIV CORNELL (US) | 2019-04-24 | — | — | EP | disclosed |
| US-20120252699-A1 | COUPLED RECOGNITION/DETECTION SYSTEM FOR IN VIVO AND IN VITRO USE | CORNELL UNIVERSITY (US) | 2012-10-04 | — | — | US | disclosed |
| EP-2398775-A1 | COUPLED RECOGNITION/DETECTION SYSTEM FOR IN VIVO AND IN VITRO USE | Cornell University (US) | 2011-12-28 | — | — | EP | disclosed |
| WO-2010096584-A1 | COUPLED RECOGNITION/DETECTION SYSTEM FOR IN VIVO AND IN VITRO USE | CORNELL UNIVERSITY (US) | 2010-08-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11629131-B2 | Coupled recognition/detection system for in vivo and in vitro use | DCLRE1B, TLR9, APEX1 | IGF1R 1945/4885MAPT 4039/4885KMT2A 2945/4885 |
| US-10316000-B2 | Coupled recognition/detection system for in vivo and in vitro use | DCLRE1B, TLR9, APEX1 | IGF1R 1945/4885MAPT 4039/4885KMT2A 2945/4885 |
| US-20120252699-A1 | COUPLED RECOGNITION/DETECTION SYSTEM FOR IN VIVO AND IN VITRO USE | DCLRE1B, TLR9, APEX1 | IGF1R 1945/4885MAPT 4039/4885KMT2A 2945/4885 |
| US-20190185434-A1 | COUPLED RECOGNITION/DETECTION SYSTEM FOR IN VIVO AND IN VITRO USE | DCLRE1B, TLR9, APEX1 | IGF1R 1945/4885MAPT 4039/4885KMT2A 2945/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.