Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN7A | Q01118 | 6/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.46 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.44 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 4/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.36 |
| ▸ | DRD1 | P21728 | 2/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3722567 | 1.00 | SCN7A (0.46) | SCN7AKCNH2SCN5ASCN2ASCN8A | |
| SCHEMBL3717035 | 0.86 | SCN7A (0.46) | SCN7AKCNH2SCN5ASCN2ASCN8A | |
| SCHEMBL3720434 | 0.86 | SCN7A (0.46) | SCN7AKCNH2SCN5ASCN2ASCN8A | |
| SCHEMBL3717668 | 0.85 | CYP1A2 (0.37) | SCN7AMAP4K4SCN9A | |
| SCHEMBL3724310 | 0.84 | SCN7A (0.49) | SCN7AKCNH2SCN5ASCN2ASCN8A | |
| SCHEMBL3717955 | 0.84 | SCN7A (0.49) | SCN7AKCNH2SCN5ASCN2ASCN8A | |
| SCHEMBL3720646 | 0.82 | GLA (0.43) | MAP4K4 | |
| SCHEMBL3719592 | 0.82 | SLC5A2 (0.33) | SCN7AKCNH2SCN5ASCN2ASCN8A | |
| SCHEMBL3720725 | 0.82 | ACACB (0.38) | MAP4K4 | |
| SCHEMBL3720741 | 0.81 | FFAR4 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |