Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN7A | Q01118 | 6/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.47 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.46 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 7/20 | 0.45 |
| ▸ | ACACB | O00763 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3717955 | 1.00 | SCN7A (0.49) | SCN7AKCNH2MTNR1AMTNR1BSCN5A | |
| SCHEMBL3726805 | 0.86 | MTNR1A (0.49) | MTNR1AMTNR1BSCN9AACACBPKM | |
| SCHEMBL3719881 | 0.84 | MTNR1A (0.46) | MTNR1AMTNR1BSCN9AACACB | |
| SCHEMBL3722567 | 0.84 | SCN7A (0.46) | SCN7AKCNH2SCN5ASCN2ASCN8A | |
| SCHEMBL3720552 | 0.84 | SCN7A (0.46) | SCN7AKCNH2SCN5ASCN2ASCN8A | |
| SCHEMBL3727352 | 0.84 | MTNR1A (0.50) | MTNR1AMTNR1BSCN9AACACB | |
| SCHEMBL3718230 | 0.83 | MTNR1A (0.48) | MTNR1AMTNR1BSCN9AACACB | |
| SCHEMBL3720862 | 0.83 | ACACB (0.53) | SCN7AKCNH2MTNR1AMTNR1BSCN5A | |
| SCHEMBL3724603 | 0.82 | MTNR1A (0.47) | MTNR1AMTNR1BSCN9A | |
| SCHEMBL3720434 | 0.82 | SCN7A (0.46) | SCN7AKCNH2SCN5ASCN2ASCN8A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | claimed |
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |