Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NCF1 | P14598 | 4/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3724196 | 0.90 | KEAP1 (0.41) | GLASMN1; SMN2MAP4K4 | |
| SCHEMBL3718613 | 0.89 | HRH3 (0.41) | GLASMN1; SMN2 | |
| SCHEMBL3722047 | 0.88 | GLA (0.42) | GLASMN1; SMN2NCF1TLR8HTR1A | |
| SCHEMBL3718574 | 0.88 | GLA (0.53) | GLASMN1; SMN2NCF1TLR8CSNK2A1 | |
| SCHEMBL3717292 | 0.87 | MCHR1 (0.36) | GLASMN1; SMN2NCF1MAP4K4MAPT | |
| SCHEMBL3720293 | 0.87 | GLA (0.42) | GLASMN1; SMN2NCF1TLR8HTR1A | |
| SCHEMBL3720725 | 0.86 | ACACB (0.38) | GLASMN1; SMN2TLR8MAP4K4MAPT | |
| SCHEMBL3720757 | 0.85 | PPARG (0.38) | NCF1TLR8MAP4K4MAPT | |
| SCHEMBL3720741 | 0.84 | FFAR4 (0.36) | GLASMN1; SMN2 | |
| SCHEMBL3719927 | 0.83 | ACACB (0.36) | NCF1TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |