Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 2/20 | 0.53 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | ACACA | Q13085 | 1/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3720271 | 0.84 | PDE4B (0.42) | PDE4BSCN7AKCNH2SCN9AMAPT | |
| SCHEMBL3724294 | 0.84 | PDE4B (0.55) | PDE4BSCN7AKCNH2SCN9AMAPT | |
| SCHEMBL3720536 | 0.83 | PDE4B (0.42) | PDE4BSCN7AKCNH2SCN9AMAPT | |
| SCHEMBL3719889 | 0.83 | PDE4B (0.42) | PDE4BSMN1; SMN2LMNACYP1A2HIF1A | |
| SCHEMBL3717735 | 0.81 | PDE4B (0.57) | PDE4BSCN7AKCNH2SCN9AMAPT | |
| SCHEMBL3720768 | 0.81 | ACACB (0.45) | ACACBACACA | |
| SCHEMBL3720024 | 0.81 | PDE4B (0.53) | PDE4BSCN7AKCNH2SCN9AMAPT | |
| SCHEMBL3719988 | 0.81 | PDE4B (0.53) | PDE4BSCN7AKCNH2SCN9AMAPT | |
| SCHEMBL3720771 | 0.79 | MTNR1A (0.54) | SCN9AMAPTHPGDSMN1; SMN2LMNA | |
| SCHEMBL3718630 | 0.78 | PDE4B (0.54) | PDE4BSCN7AKCNH2SCN9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |