Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NCF1 | P14598 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | TEC | P42680 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3717827 | 0.89 | ALDH1A1 (0.49) | GLASMN1; SMN2LMNATLR8ALDH1A1 | |
| SCHEMBL3720646 | 0.87 | GLA (0.43) | GLASMN1; SMN2NCF1TLR8HTR1A | |
| SCHEMBL3721858 | 0.87 | GLA (0.43) | GLASMN1; SMN2LMNATLR8 | |
| SCHEMBL3717279 | 0.87 | GLA (0.57) | GLASMN1; SMN2TLR8TECALDH1A1 | |
| SCHEMBL3718574 | 0.86 | GLA (0.53) | GLASMN1; SMN2NCF1TLR8TEC | |
| SCHEMBL3722047 | 0.86 | GLA (0.42) | GLASMN1; SMN2LMNANCF1TLR8 | |
| SCHEMBL3720365 | 0.84 | MAPT (0.41) | SMN1; SMN2LMNATECALDH1A1RAB9A | |
| SCHEMBL3720117 | 0.84 | LMNA (0.39) | GLASMN1; SMN2LMNATLR8TEC | |
| SCHEMBL3723856 | 0.83 | LTA4H (0.49) | GLASMN1; SMN2LMNAHTTHSD17B10 | |
| SCHEMBL3717388 | 0.83 | ACACB (0.40) | LMNAHTTHSD17B10NCF1TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |