Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 3/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 3/20 | 0.33 |
| ▸ | ACACB | O00763 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | TAAR5 | O14804 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3720741 | 0.91 | FFAR4 (0.36) | GLASMN1; SMN2CYP1A2CYP3A4TSHR | |
| SCHEMBL3719226 | 0.86 | GPBAR1 (0.35) | GPBAR1CYSLTR1CARM1PRMT6ACACB | |
| SCHEMBL3721521 | 0.85 | MTNR1A (0.48) | SMN1; SMN2ACACB | |
| SCHEMBL3720725 | 0.84 | ACACB (0.38) | GLASMN1; SMN2CYP1A2CYP3A4TSHR | |
| SCHEMBL3720743 | 0.84 | CYP1A2 (0.35) | GLASMN1; SMN2CYP1A2CYP3A4TSHR | |
| SCHEMBL3720646 | 0.83 | GLA (0.43) | GLASMN1; SMN2 | |
| SCHEMBL3720648 | 0.81 | MAPT (0.36) | GPBAR1CYSLTR1TSHRSLC2A1MCHR1 | |
| SCHEMBL3717668 | 0.81 | CYP1A2 (0.37) | GLASMN1; SMN2CYP1A2CYP3A4TSHR | |
| SCHEMBL3719835 | 0.80 | FFAR4 (0.36) | GLASMN1; SMN2CYP1A2CYP3A4TSHR | |
| SCHEMBL3719225 | 0.80 | PDE4B (0.46) | GPBAR1CYSLTR1SMN1; SMN2TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |