Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | ESR1 | P03372 | 5/20 | 0.64 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.57 |
| ▸ | LTA4H | P09960 | 2/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.56 |
| ▸ | PSMB1 | P20618 | 4/20 | 0.55 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.55 |
| ▸ | PSMB2 | P49721 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3720426 | 0.87 | KDM4E (0.70) | KDM4EPOLBESR1ESR2ALDH1A1 | |
| SCHEMBL2322277 | 0.81 | KDM4E (0.63) | KDM4EPOLBESR1ESR2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7054130 | 0.80 | KDM4E (0.73) | KDM4EPOLBESR1ESR2ALDH1A1 | |
| SCHEMBL9939631 | 0.79 | KDM4E (0.65) | KDM4EPOLBESR1ESR2ALDH1A1 | |
| SCHEMBL21408361 | 0.79 | KDM4E (0.72) | KDM4EPOLBESR1ESR2ALDH1A1 | |
| SCHEMBL8909081 | 0.79 | KDM4E (0.64) | KDM4EPOLBESR1ESR2ALDH1A1 | |
| SCHEMBL7564110 | 0.79 | KDM4E (0.82) | KDM4EPOLBALDH1A1SMN1; SMN2HRH3 | |
| SCHEMBL1359959 | 0.78 | ESR1 (0.76) | KDM4EESR1ESR2HRH3LTA4H | |
| SCHEMBL14970686 | 0.78 | LTA4H (0.87) | HRH3LTA4HPTGS2PSMB1PSMB5 | |
| SCHEMBL5438744 | 0.78 | LTA4H (0.87) | HRH3LTA4HPTGS2PSMB1PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |