Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.82 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.82 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.82 |
| ▸ | POLB | P06746 | 1/20 | 0.72 |
| ▸ | HRH3 | Q9Y5N1 | 15/20 | 0.64 |
| ▸ | ACHE | P22303 | 1/20 | 0.63 |
| ▸ | RAD52 | P43351 | 1/20 | 0.63 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14970474 | 0.95 | KDM4E (0.75) | KDM4EALDH1A1SMN1; SMN2POLBHRH3 | |
| SCHEMBL7398924 | 0.94 | KDM4E (0.73) | KDM4EALDH1A1SMN1; SMN2POLBHRH3 | |
| SCHEMBL7396432 | 0.94 | KDM4E (0.73) | KDM4EALDH1A1SMN1; SMN2POLBHRH3 | |
| SCHEMBL7399802 | 0.94 | KDM4E (0.73) | KDM4EALDH1A1SMN1; SMN2POLBHRH3 | |
| Hydrochloric Acid SCHEMBL7594910 | 0.93 | KDM4E (0.71) | KDM4EALDH1A1SMN1; SMN2POLBHRH3 | |
| Hydrochloric Acid SCHEMBL7395361 | 0.93 | KDM4E (0.71) | KDM4EALDH1A1SMN1; SMN2POLBHRH3 | |
| SCHEMBL1387405 | 0.89 | KDM4E (0.67) | KDM4EALDH1A1SMN1; SMN2POLBHRH3 | |
| Hydrochloric Acid SCHEMBL7443521 | 0.88 | KDM4E (0.65) | KDM4EALDH1A1SMN1; SMN2POLBHRH3 | |
| SCHEMBL3581300 | 0.87 | KDM4E (0.64) | KDM4EALDH1A1SMN1; SMN2POLBHRH3 | |
| SCHEMBL9528149 | 0.86 | KDM4E (0.62) | KDM4EALDH1A1SMN1; SMN2POLBHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1190710-A1 | PREVENTIVE OR THERAPEUTIC DRUGS FOR DIABETES | SHIONOGI & CO., LTD. (JP) | 2002-03-27 | — | — | EP | disclosed |