Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 2/20 | 0.36 |
| ▸ | RAF1 | P04049 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3718309 | 0.90 | MTNR1A (0.49) | MTNR1AMTNR1BMAPTKDM4EALDH1A1 | |
| SCHEMBL3717456 | 0.85 | MTNR1A (0.50) | MTNR1AMTNR1BMAPTKDM4EALDH1A1 | |
| SCHEMBL3719941 | 0.84 | MTNR1A (0.51) | MTNR1AMTNR1BMAPTKDM4EALDH1A1 | |
| SCHEMBL3721521 | 0.83 | MTNR1A (0.48) | MTNR1AMTNR1BPKMCES2SCN9A | |
| SCHEMBL3727352 | 0.81 | MTNR1A (0.50) | MTNR1AMTNR1BMAPTKDM4EALDH1A1 | |
| SCHEMBL3726805 | 0.80 | MTNR1A (0.49) | MTNR1AMTNR1BMAPTKDM4EALDH1A1 | |
| SCHEMBL3720672 | 0.80 | ACACB (0.38) | — | |
| SCHEMBL3727615 | 0.80 | MTNR1A (0.48) | MTNR1AMTNR1BMAPTKDM4EALDH1A1 | |
| SCHEMBL3720627 | 0.79 | MTNR1A (0.50) | MTNR1AMTNR1BMAPTKDM4EALDH1A1 | |
| SCHEMBL3720171 | 0.79 | MTNR1A (0.57) | MTNR1AMTNR1BPOLBMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |