Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | THRA | P10827 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | LSS | P48449 | 1/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17912821 | 0.83 | LTA4H (0.50) | KDM4EALDH1A1SMN1; SMN2THRATHRB | |
| SCHEMBL13744509 | 0.82 | DRD2 (0.55) | KDM4EHRH3ALDH1A1SMN1; SMN2THRA | |
| SCHEMBL26417385 | 0.81 | KDM4E (0.53) | KDM4EHRH3ALDH1A1SMN1; SMN2THRB | |
| SCHEMBL3717444 | 0.80 | LTA4H (0.50) | KDM4EALDH1A1THRATHRBKMT2A | |
| SCHEMBL9699878 | 0.79 | NR5A1 (0.59) | THRATHRB | |
| SCHEMBL9697687 | 0.79 | NR5A1 (0.59) | THRATHRB | |
| SCHEMBL9697405 | 0.79 | NR5A1 (0.59) | THRATHRB | |
| SCHEMBL27501496 | 0.79 | FFAR1 (0.50) | KDM4EALDH1A1SMN1; SMN2TDP1MAPT | |
| SCHEMBL9736630 | 0.79 | NR5A1 (0.59) | THRATHRB | |
| SCHEMBL28758417 | 0.78 | KDR (0.47) | KDM4EALDH1A1SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |