Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.76 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.76 |
| ▸ | POLA1 | P09884 | 1/20 | 0.76 |
| ▸ | POLG | P54098 | 1/20 | 0.76 |
| ▸ | FAP | Q12884 | 1/20 | 0.76 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.65 |
| ▸ | NSD3 | Q9BZ95 | 2/20 | 0.49 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.48 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | PI4KA | P42356 | 1/20 | 0.46 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.46 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.46 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28797052 | 0.88 | FGFR1 (0.74) | SLC22A6ABCB11POLA1POLGFAP | |
| Adefovir Dipivoxil SCHEMBL29372789 | 0.86 | FAP (1.00) | SLC22A6ABCB11POLA1POLGFAP | |
| Adefovir Dipivoxil SCHEMBL29729 | 0.86 | FAP (1.00) | SLC22A6ABCB11POLA1POLGFAP | |
| Adefovir Dipivoxil SCHEMBL5845498 | 0.86 | FAP (1.00) | SLC22A6ABCB11POLA1POLGFAP | |
| Adefovir SCHEMBL28809752 | 0.86 | FGFR1 (0.78) | SLC22A6ABCB11POLA1POLGFAP | |
| Adefovir Dipivoxil SCHEMBL3719079 | 0.85 | FAP (0.98) | SLC22A6ABCB11POLA1POLGFAP | |
| Adefovir Dipivoxil SCHEMBL3646944 | 0.85 | FAP (0.98) | SLC22A6ABCB11POLA1POLGFAP | |
| SCHEMBL20718818 | 0.85 | SLC22A6 (0.77) | SLC22A6ABCB11POLA1POLGFAP | |
| Adefovir Dipivoxil SCHEMBL457147 | 0.83 | FAP (0.93) | SLC22A6ABCB11POLA1POLGFAP | |
| Adefovir Dipivoxil SCHEMBL3745803 | 0.83 | FAP (0.93) | SLC22A6ABCB11POLA1POLGFAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010110506-A1 | DH-TYPE CRYSTALLINE FORM OF ADEFOVIR DIPIVOXIL, PREPARING METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION FOR ANTIVIRAL AGENT COMPRISING THE SAME | DAE HE CHEMICAL CO.,LTD. (KR) | 2010-09-30 | — | — | WO | disclosed |