Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 16/20 | 0.51 |
| ▸ | ACACA | Q13085 | 11/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3726184 | 0.88 | ACACB (0.66) | ACACBACACAALOX5 | |
| SCHEMBL3727288 | 0.87 | ACACB (0.46) | ACACBACACAALOX5 | |
| SCHEMBL3720090 | 0.87 | ACACB (0.46) | ACACBACACAALOX5 | |
| SCHEMBL13076810 | 0.85 | ACACB (0.58) | ACACBACACA | |
| SCHEMBL3726452 | 0.85 | ACACB (0.59) | ACACBACACAALOX5 | |
| SCHEMBL13077226 | 0.84 | ACACB (0.55) | ACACBACACAALOX5 | |
| SCHEMBL13077236 | 0.83 | ACACB (0.66) | ACACBACACAALOX5 | |
| SCHEMBL3724464 | 0.83 | ACACB (0.60) | ACACBACACA | |
| SCHEMBL3720169 | 0.82 | MMP9 (0.51) | ACACBACACAALOX5 | |
| SCHEMBL3726321 | 0.82 | CYP2C9 (0.52) | ACACBACACAALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |