Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | ACACB | O00763 | 11/20 | 0.47 |
| ▸ | ACACA | Q13085 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3726452 | 0.85 | ACACB (0.59) | ALOX5ACACBACACA | |
| SCHEMBL14986294 | 0.85 | MMP9 (0.69) | MMP9ALOX5ACACBACACAMEN1 | |
| SCHEMBL7734521 | 0.85 | MMP9 (0.69) | MMP9ALOX5ACACBACACAMEN1 | |
| SCHEMBL15022611 | 0.82 | ACACB (0.54) | ACACBACACA | |
| SCHEMBL6966307 | 0.82 | ACACB (0.54) | ACACBACACA | |
| SCHEMBL3721881 | 0.82 | CYP1A2 (0.54) | MMP9ALOX5ACACBACACA | |
| SCHEMBL3720744 | 0.82 | ACACB (0.51) | ALOX5ACACBACACA | |
| SCHEMBL3727288 | 0.81 | ACACB (0.46) | ALOX5ACACBACACAMEN1KMT2A | |
| SCHEMBL3720090 | 0.81 | ACACB (0.46) | ALOX5ACACBACACA | |
| SCHEMBL3719875 | 0.81 | ALOX5 (0.74) | ALOX5ACACBCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |