Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 3/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17540921 | 0.86 | KMT2A (0.46) | ADRB2ADRB1MAOBKMT2ASMN1; SMN2 | |
| SCHEMBL27460759 | 0.83 | SIGMAR1 (0.45) | ADRB2ADRB1MAOBKMT2ASMN1; SMN2 | |
| SCHEMBL1083387 | 0.83 | ADRB2 (0.61) | ADRB2ADRB1MAOBKMT2AHSD17B10 | |
| SCHEMBL28221888 | 0.81 | ADRB2 (0.47) | ADRB2ADRB1MAOBKMT2ASMN1; SMN2 | |
| SCHEMBL3720155 | 0.80 | ADRB2 (0.46) | ADRB2ADRB1KMT2ASMN1; SMN2MAOA | |
| SCHEMBL339174 | 0.79 | PDK2 (0.50) | ADRB2ADRB1MAOBKMT2AMAOA | |
| SCHEMBL2221195 | 0.79 | NQO1 (0.50) | KMT2ATSHRHSD17B10MAPTHPGD | |
| SCHEMBL2608847 | 0.79 | MAPT (0.43) | MAOBKMT2ASMN1; SMN2MAOATSHR | |
| SCHEMBL19962879 | 0.79 | MAOB (0.41) | MAOBKMT2ASMN1; SMN2MAOAMAPT | |
| SCHEMBL3721637 | 0.79 | ADRB2 (0.45) | ADRB2ADRB1MAPTPOLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |