Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ESRRA | P11474 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3721868 | 0.92 | PDE4B (0.48) | PDE4BALDH1A1TSHRSCN7AKCNH2 | |
| SCHEMBL3716835 | 0.89 | PDE4B (0.53) | PDE4BALDH1A1TSHRSCN7AKCNH2 | |
| SCHEMBL3720788 | 0.88 | PDE4B (0.52) | PDE4BALDH1A1TSHRSCN7AKCNH2 | |
| SCHEMBL3724294 | 0.86 | PDE4B (0.55) | PDE4BALDH1A1TSHRSCN7AKCNH2 | |
| SCHEMBL3719669 | 0.85 | PDE4B (0.49) | PDE4BALDH1A1TSHRSCN7AKCNH2 | |
| SCHEMBL3717722 | 0.85 | PDE4B (0.45) | PDE4BALDH1A1TSHRSCN7AKCNH2 | |
| SCHEMBL3719225 | 0.84 | PDE4B (0.46) | PDE4BALDH1A1TSHRSCN7AKCNH2 | |
| SCHEMBL3720702 | 0.82 | PDE4B (0.57) | PDE4BALDH1A1TSHRSCN7AKCNH2 | |
| SCHEMBL3717769 | 0.82 | PDE4B (0.48) | PDE4BALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL3719548 | 0.82 | PDE4B (0.48) | PDE4BALDH1A1TSHRSCN7AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |