Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 2/20 | 0.57 |
| ▸ | ESRRA | P11474 | 2/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.41 |
| ▸ | SCN7A | Q01118 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3721089 | 0.82 | PDE4B (0.53) | PDE4BESRRASCN9ASCN7AKCNH2 | |
| SCHEMBL3717735 | 0.81 | PDE4B (0.57) | PDE4BSCN9ASCN7AKCNH2CYP2A6 | |
| SCHEMBL3720071 | 0.79 | PDE4B (0.49) | PDE4BESRRASCN9ASCN7AKCNH2 | |
| SCHEMBL3717034 | 0.79 | SCN7A (0.49) | PDE4BSCN7AKCNH2PPARGSMN1; SMN2 | |
| SCHEMBL3720433 | 0.79 | SCN7A (0.49) | PDE4BSCN7AKCNH2PPARGSMN1; SMN2 | |
| SCHEMBL3721868 | 0.79 | PDE4B (0.48) | PDE4BSCN9ASCN7AKCNH2CYP2A6 | |
| SCHEMBL28248095 | 0.79 | NPC1 (0.44) | ESRRASMN1; SMN2GAATSHRNPSR1 | |
| SCHEMBL3724294 | 0.79 | PDE4B (0.55) | PDE4BSCN9ASCN7AKCNH2SMN1; SMN2 | |
| SCHEMBL3720703 | 0.78 | PDE4B (0.36) | PDE4BESRRASCN9ASCN7AKCNH2 | |
| SCHEMBL3718481 | 0.78 | PDE4B (0.54) | PDE4BSCN9APPARGSMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |