Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Citric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 4/20 | 0.94 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Citric Acid SCHEMBL260176 | 1.00 | CA4 (0.94) | CA4CASP1FFAR3HDAC3HDAC1 | |
| Citric Acid SCHEMBL372670 | 1.00 | CA4 (0.94) | CA4CASP1FFAR3HDAC3HDAC1 | |
| Citric Acid SCHEMBL6692872 | 1.00 | CA4 (0.94) | CA4CASP1FFAR3HDAC3HDAC1 | |
| Citric Acid SCHEMBL3775695 | 1.00 | CA4 (0.94) | CA4CASP1FFAR3HDAC3HDAC1 | |
| Citric Acid SCHEMBL6692875 | 1.00 | CA4 (0.94) | CA4CASP1FFAR3HDAC3HDAC1 | |
| Citric Acid SCHEMBL25212993 | 1.00 | CA4 (0.94) | CA4CASP1FFAR3HDAC3HDAC1 | |
| Citric Acid SCHEMBL372534 | 1.00 | CA4 (0.94) | CA4CASP1FFAR3HDAC3HDAC1 | |
| Citric Acid SCHEMBL372244 | 1.00 | CA4 (0.94) | CA4CASP1FFAR3HDAC3HDAC1 | |
| Citric Acid SCHEMBL20917176 | 1.00 | CA4 (0.94) | CA4CASP1FFAR3HDAC3HDAC1 | |
| Citric Acid SCHEMBL5163322 | 1.00 | CA4 (0.94) | CA4CASP1FFAR3HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 667 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119881299-A | Kit for detecting transferrin and application thereof | 昆明理工大学 | 2025-04-25 | — | — | CN | claimed |
| CN-119506994-A | Ceramic relay shell secondary metallization nickel electroplating pretreatment process | 娄底市鑫伟达金属材料有限公司 | 2025-02-25 | — | — | CN | claimed |
| WO-2024250495-A1 | WATER-BASED INK AND PREPARATION METHOD THEREFOR | 江苏唐彩新材料科技股份有限公司 | 2024-12-12 | — | — | WO | claimed |
| CN-118962115-A | Lateral flow chromatography kit for quantitatively detecting salmonella enteritidis | 齐鲁工业大学(山东省科学院) | 2024-11-15 | — | — | CN | claimed |
| CN-118703339-A | Edible fusarium | 泰兴市东圣生物科技有限公司 | 2024-09-27 | — | — | CN | claimed |
| CN-118546386-A | In-situ photoelectrochemical heterostructure material based on metal oxide and preparation method thereof | 福州大学 | 2024-08-27 | — | — | CN | claimed |
| CN-118185370-A | Methacrylate monomer type fluorescent ink | 广东汇泉联骏化学工业有限公司 | 2024-06-14 | — | — | CN | claimed |
| CN-118064418-A | L-arabinose isomerase and method for preparing D-tagatose by using same | 天津科技大学 | 2024-05-24 | — | — | CN | claimed |
| CN-118026713-A | Carbon fiber reinforced silicon carbide ceramic composite material and direct writing forming method | 汕头大学 | 2024-05-14 | — | — | CN | claimed |
| US-11929513-B2 | Fuel cells, bifunctional catalysts thereof, and preparation methods therefor | HARBIN INSTITUTE OF TECHNOLOGY, SHENZHEN (CN) | 2024-03-12 | — | — | US | claimed |
| EP-1133549-A1 | DETERGENT COMPOSITIONS | UNILEVER PLC (GB) | 2001-09-19 | — | — | EP | claimed |
| US-6242403-B1 | TABLET FROM COMPACTED (A) PARTICLES CONTAINING AT LEAST 60% BY WEIGHT OF NON-SOAP ANIONIC DETERGENT AND (B) PARTICLES CONTAINING AT LEAST 80% OF THEIR OWN WEIGHT OF ONE OR MORE WATER-SOLUBLE MATERIALS | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. | 2001-06-05 | — | — | US | claimed |
| EP-1071742-A1 | WATER-SOFTENING AND DETERGENT COMPOSITIONS | UNILEVER PLC (GB) | 2001-01-31 | — | — | EP | claimed |
| EP-1027421-A1 | DETERGENT COMPOSITIONS IN TABLET FORM | UNILEVER PLC (GB) | 2000-08-16 | — | — | EP | claimed |
| WO-2000038644-A1 | STABLE SOLUTION OF ZINC IONS AND BICARBONATE AND/OR CARBONATE IONS | CHURCH & DWIGHT CO., INC. (US) | 2000-07-06 | — | — | WO | claimed |
| WO-2000032740-A1 | DETERGENT COMPOSITIONS IN TABLET FORM | UNILEVER PLC (GB) | 2000-06-08 | — | — | WO | claimed |
| WO-2000032741-A1 | DETERGENT COMPOSITIONS | UNILEVER PLC (GB) | 2000-06-08 | — | — | WO | claimed |
| WO-1999053014-A1 | WATER-SOFTENING AND DETERGENT COMPOSITIONS | UNILEVER PLC (GB) | 1999-10-21 | — | — | WO | claimed |
| WO-1999020730-A1 | DETERGENT COMPOSITIONS IN TABLET FORM | UNILEVER PLC (GB) | 1999-04-29 | — | — | WO | claimed |
| US-5595687-A | INJECTABLE FLUOROCARBON EMULSION USEFUL IN CORONARY ANGIOPLASTY, CANCER THERAPY | THOMAS JEFFERSON UNIVERSITY (US) | 1997-01-21 | — | — | US | claimed |