Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | IDO1 | P14902 | 1/20 | 0.51 |
| ▸ | CTSK | P43235 | 4/20 | 0.50 |
| ▸ | CTSS | P25774 | 3/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | MMP3 | P08254 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | AKT1 | P31749 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6335082 | 1.00 | MEN1 (0.57) | MEN1GAAKMT2AIDO1CTSK | |
| SCHEMBL24003388 | 0.87 | MEN1 (0.69) | MEN1GAAKMT2AIDO1CTSK | |
| SCHEMBL9074865 | 0.87 | MEN1 (0.69) | MEN1GAAKMT2AIDO1CTSK | |
| SCHEMBL15159959 | 0.85 | ATM (0.62) | MEN1GAAKMT2ACTSKCTSS | |
| SCHEMBL7428131 | 0.84 | MEN1 (0.53) | MEN1GAAKMT2AIDO1CTSK | |
| SCHEMBL10188447 | 0.83 | ATM (0.56) | IDO1CTSKCTSSCTSLCTSB | |
| SCHEMBL6775479 | 0.83 | SIGMAR1 (0.54) | MEN1GAAKMT2AIDO1CTSK | |
| SCHEMBL6491658 | 0.82 | MEN1 (0.61) | MEN1GAAKMT2AIDO1CTSK | |
| SCHEMBL6494079 | 0.82 | MEN1 (0.61) | MEN1GAAKMT2AIDO1CTSK | |
| SCHEMBL6500581 | 0.82 | MEN1 (0.61) | MEN1GAAKMT2AIDO1CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010139707-A1 | 2-AMINOOXAZOLINES AS TAAR1 LIGANDS | F. HOFFMANN-LA ROCHE AG (CH) | 2010-12-09 | — | — | WO | disclosed |