SCHEMBL372234

SCHEMBL372234

CCCCCCN[Si](OCCCC)(OCCCC)OCCCC

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 8/20 0.41
TSHR P16473 2/20 0.39
ALDH1A1 P00352 1/20 0.39
ADH1B P00325 1/20 0.37
ADH1C P00326 1/20 0.37
ADH1A P07327 1/20 0.37
ADH4 P08319 1/20 0.37
ADH7 P40394 1/20 0.37
CASP2 P42575 1/20 0.36
THRB P10828 1/20 0.35
PPARA Q07869 2/20 0.33
GBA1 P04062 3/20 0.32
ADRB2 P07550 1/20 0.32
ADRB1 P08588 1/20 0.32
ADRB3 P13945 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL372817 1.00 EPHX1 (0.41) EPHX1TSHRALDH1A1ADH1BADH1C
SCHEMBL372567 1.00 EPHX1 (0.41) EPHX1TSHRALDH1A1ADH1BADH1C
SCHEMBL373024 0.98 TSHR (0.40) EPHX1TSHRALDH1A1ADH1BADH1C
SCHEMBL372566 0.91 EPHX1 (0.41) EPHX1TSHRALDH1A1ADH1BADH1C
SCHEMBL372856 0.91 EPHX1 (0.41) EPHX1TSHRALDH1A1ADH1BADH1C
SCHEMBL372767 0.91 EPHX1 (0.41) EPHX1TSHRALDH1A1ADH1BADH1C
SCHEMBL372565 0.91 TSHR (0.35) TSHRALDH1A1ADH1BADH1CADH1A
SCHEMBL372559 0.89 TSHR (0.40) EPHX1TSHRALDH1A1ADH1BADH1C
SCHEMBL372467 0.86 ADRB2 (0.35) TSHRALDH1A1ADRB2ADRB1ADRB3
SCHEMBL372739 0.84 EPHX1 (0.42) EPHX1TSHRALDH1A1ADH1BADH1C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11465570-B2 Extrusion grade perlite reinforced polypropylene polymer FORD GLOBAL TECHNOLOGIES, LLC (US) 2022-10-11 US claimed
US-20200198555-A1 EXTRUSION GRADE PERLITE REINFORCED POLYPROPYLENE POLYMER FORD GLOBAL TECHNOLOGIES, LLC (US) 2020-06-25 US claimed
US-10632936-B2 Extrusion grade perlite reinforced polypropylene polymer FORD GLOBAL TECHNOLOGIES, LLC (US) 2020-04-28 US claimed
US-20180326922-A1 EXTRUSION GRADE PERLITE REINFORCED POLYPROPYLENE POLYMER FORD GLOBAL TECHNOLOGIES, LLC (US) 2018-11-15 US claimed
US-9133281-B2 Preparation and use of functionalized elastomers in rubber compositions containing silica filler and tire components thereof THE GOODYEAR TIRE & RUBBER COMPANY (US) 2015-09-15 US claimed
US-20140155542-A1 PREPARATION AND USE OF FUNCTIONALIZED ELASTOMERS IN RUBBER COMPOSITIONS CONTAINING SILICA FILLER AND TIRE COMPONENTS THEREOF THE GOODYEAR TIRE & RUBBER COMPANY (US) 2014-06-05 US claimed
US-8357747-B2 Polymer compositions comprising fluoro elastomers and expanded perlite IMERYS FILTRATION MINERALS, INC. (US) 2013-01-22 US claimed
EP-2410025-A1 Barrier compositions Imerys Minerals Limited (GB) 2012-01-25 EP claimed
US-20100317789-A1 Polymer Compositions Comprising Fluoro Elastomers and Expanded Perlite WORLD MINERALS, INC 2010-12-16 US claimed
US-20100105824-A1 Polymer Compositions WORLD MINERALS, INC. (US) 2010-04-29 US claimed
US-20090321681-A1 Barrier Compositions IMERYS MINERALS, LTD. (GB) 2009-12-31 US claimed
EP-2115057-A1 POLYMER COMPOSITIONS COMPRISING FLUORO ELASTOMERS AND EXPANDED PERLITE World Minerals, Inc. (US) 2009-11-11 EP claimed
EP-2016139-A2 BARRIER COMPOSITIONS Imerys Minerals Limited (GB) 2009-01-21 EP claimed
WO-2008081173-A1 POLYMER COMPOSITIONS COMPRISING FLUORO ELASTOMERS AND EXPANDED PERLITE WORLD MINERALS, INC. (US) 2008-07-10 WO claimed
WO-2008053236-A1 POLYMER COMPOSITIONS WORLD MINERALS, INC. (US) 2008-05-08 WO claimed
WO-2007125312-A2 BARRIER COMPOSITIONS IMERYS MINERALS LIMITED (GB) 2007-11-08 WO claimed
EP-1809581-A1 PARTICULATE MATERIAL Imerys Minerals Limited (GB) 2007-07-25 EP claimed
WO-2007010276-A1 PARTICULATE MATERIAL IMERYS MINERALS LIMITED (GB) 2007-01-25 WO claimed
EP-4700080-A2 TALC PARTICULATE ImerTech SAS (FR) 2026-02-25 EP disclosed
US-5698619-A Aminosilane compounds in silica-filled rubber compositions THE GOODYEAR TIRE & RUBBER COMPANY (US) 1997-12-16 US disclosed