SCHEMBL372565

SCHEMBL372565

CCCCN[Si](OCCCC)(OCCCC)OCCCC

nearest known ligand 0.35

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.35
ADRB2 P07550 1/20 0.35
ADRB1 P08588 1/20 0.35
ADRB3 P13945 1/20 0.35
ACHE P22303 8/20 0.34
LMNA P02545 1/20 0.33
ATM Q13315 1/20 0.32
ADH1B P00325 1/20 0.31
ADH1C P00326 1/20 0.31
ADH1A P07327 1/20 0.31
ADH7 P40394 1/20 0.31
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA7 P43166 1/20 0.31
CA14 Q9ULX7 1/20 0.31
CYP3A4 P08684 1/20 0.31
ALDH1A1 P00352 2/20 0.31
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL373024 0.93 TSHR (0.40) TSHRADRB2ADRB1ADRB3LMNA
SCHEMBL372567 0.91 EPHX1 (0.41) TSHRADRB2ADRB1ADRB3ADH1B
SCHEMBL372817 0.91 EPHX1 (0.41) TSHRADRB2ADRB1ADRB3ADH1B
SCHEMBL372234 0.91 EPHX1 (0.41) TSHRADRB2ADRB1ADRB3ADH1B
SCHEMBL373146 0.91 TSHR (0.35) TSHRACHELMNAADH1BADH1C
SCHEMBL372467 0.91 ADRB2 (0.35) TSHRADRB2ADRB1ADRB3ACHE
SCHEMBL938350 0.85 ADRB2 (0.31) ADRB2ADRB1ADRB3
SCHEMBL372559 0.84 TSHR (0.40) TSHRLMNAADH1BADH1CADH1A
SCHEMBL372464 0.83 TSHR (0.36) TSHRACHELMNAADH1BADH1C
SCHEMBL372743 0.83 ADRB2 (0.36) TSHRADRB2ADRB1ADRB3LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11465570-B2 Extrusion grade perlite reinforced polypropylene polymer FORD GLOBAL TECHNOLOGIES, LLC (US) 2022-10-11 US claimed
US-20200198555-A1 EXTRUSION GRADE PERLITE REINFORCED POLYPROPYLENE POLYMER FORD GLOBAL TECHNOLOGIES, LLC (US) 2020-06-25 US claimed
US-10632936-B2 Extrusion grade perlite reinforced polypropylene polymer FORD GLOBAL TECHNOLOGIES, LLC (US) 2020-04-28 US claimed
US-20180326922-A1 EXTRUSION GRADE PERLITE REINFORCED POLYPROPYLENE POLYMER FORD GLOBAL TECHNOLOGIES, LLC (US) 2018-11-15 US claimed
US-9133281-B2 Preparation and use of functionalized elastomers in rubber compositions containing silica filler and tire components thereof THE GOODYEAR TIRE & RUBBER COMPANY (US) 2015-09-15 US claimed
US-20140155542-A1 PREPARATION AND USE OF FUNCTIONALIZED ELASTOMERS IN RUBBER COMPOSITIONS CONTAINING SILICA FILLER AND TIRE COMPONENTS THEREOF THE GOODYEAR TIRE & RUBBER COMPANY (US) 2014-06-05 US claimed
US-8357747-B2 Polymer compositions comprising fluoro elastomers and expanded perlite IMERYS FILTRATION MINERALS, INC. (US) 2013-01-22 US claimed
EP-2410025-A1 Barrier compositions Imerys Minerals Limited (GB) 2012-01-25 EP claimed
US-20100317789-A1 Polymer Compositions Comprising Fluoro Elastomers and Expanded Perlite WORLD MINERALS, INC 2010-12-16 US claimed
US-20100105824-A1 Polymer Compositions WORLD MINERALS, INC. (US) 2010-04-29 US claimed
US-20090321681-A1 Barrier Compositions IMERYS MINERALS, LTD. (GB) 2009-12-31 US claimed
EP-2115057-A1 POLYMER COMPOSITIONS COMPRISING FLUORO ELASTOMERS AND EXPANDED PERLITE World Minerals, Inc. (US) 2009-11-11 EP claimed
EP-2016139-A2 BARRIER COMPOSITIONS Imerys Minerals Limited (GB) 2009-01-21 EP claimed
WO-2008081173-A1 POLYMER COMPOSITIONS COMPRISING FLUORO ELASTOMERS AND EXPANDED PERLITE WORLD MINERALS, INC. (US) 2008-07-10 WO claimed
WO-2008053236-A1 POLYMER COMPOSITIONS WORLD MINERALS, INC. (US) 2008-05-08 WO claimed
WO-2007125312-A2 BARRIER COMPOSITIONS IMERYS MINERALS LIMITED (GB) 2007-11-08 WO claimed
EP-1809581-A1 PARTICULATE MATERIAL Imerys Minerals Limited (GB) 2007-07-25 EP claimed
WO-2007010276-A1 PARTICULATE MATERIAL IMERYS MINERALS LIMITED (GB) 2007-01-25 WO claimed
EP-4700080-A2 TALC PARTICULATE ImerTech SAS (FR) 2026-02-25 EP disclosed
US-5698619-A Aminosilane compounds in silica-filled rubber compositions THE GOODYEAR TIRE & RUBBER COMPANY (US) 1997-12-16 US disclosed