Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 11/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 7/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13191398 | 0.90 | BDKRB1 (0.45) | BDKRB1CNR1 | |
| Trifluoroacetic Acid SCHEMBL3718216 | 0.87 | CNR1 (0.47) | BDKRB1CNR1 | |
| SCHEMBL13191628 | 0.86 | BDKRB1 (0.45) | BDKRB1CNR1 | |
| SCHEMBL3728527 | 0.85 | MEN1 (0.42) | BDKRB1MEN1MAPK1KMT2A | |
| SCHEMBL13191246 | 0.84 | BDKRB1 (0.37) | BDKRB1 | |
| SCHEMBL3728529 | 0.83 | MEN1 (0.43) | BDKRB1MEN1MAPK1KMT2A | |
| SCHEMBL12238935 | 0.82 | MEN1 (0.46) | BDKRB1MEN1MAPK1KMT2A | |
| SCHEMBL3729328 | 0.82 | BDKRB1 (0.36) | BDKRB1CNR1 | |
| SCHEMBL13191590 | 0.81 | CNR1 (0.47) | BDKRB1CNR1 | |
| SCHEMBL3718987 | 0.81 | LIMK1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010097373-A1 | COMPOUNDS FOR USE AS BRADYKININ B1 ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-02 | — | — | WO | disclosed |
| WO-2010097373-A1 | COMPOUNDS FOR USE AS BRADYKININ B1 ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-02 | — | — | WO | disclosed |