Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 13/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.50 |
| ▸ | GRM5 | P41594 | 5/20 | 0.47 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3032826 | 0.82 | NPY5R (0.54) | NPY5RKCNH2 | |
| SCHEMBL3041083 | 0.82 | NPY5R (0.54) | NPY5RKCNH2 | |
| SCHEMBL3032824 | 0.82 | NPY5R (0.54) | NPY5RKCNH2 | |
| Lithium Ion SCHEMBL3026578 | 0.81 | NPY5R (0.52) | NPY5RKCNH2 | |
| SCHEMBL13079376 | 0.77 | GRM5 (0.62) | NPY5RKCNH2GRM5 | |
| SCHEMBL3032395 | 0.77 | NPY5R (0.51) | NPY5RKCNH2 | |
| SCHEMBL4022146 | 0.76 | NPY5R (0.53) | NPY5RGRM5 | |
| SCHEMBL4026062 | 0.73 | NPY5R (0.75) | NPY5R | |
| SCHEMBL4026064 | 0.73 | NPY5R (0.75) | NPY5R | |
| SCHEMBL4023059 | 0.72 | NPY5R (0.75) | NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2139861-A1 | BENZIMIDAZOLES WITH A HETERO SPIRO-DECANE RESIDUE AS NPY-Y5 ANTAGONISTS | Glaxo Group Limited (GB) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008129007-A1 | BENZIMIDAZOLES WITH A HETERO SPIRO-DECANE RESIDUE AS NPY-Y5 ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2008-10-30 | — | — | WO | disclosed |