Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CTSV | O60911 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.40 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | DTYMK | P23919 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1740988 | 0.82 | ALDH1A1 (0.46) | ALDH1A1CYP3A4ALOX15TDP1LMNA | |
| SCHEMBL9381233 | 0.82 | ALDH1A1 (0.64) | ALDH1A1CYP3A4ALOX15TDP1LMNA | |
| SCHEMBL2785910 | 0.81 | ALDH1A1 (0.56) | ALDH1A1CYP3A4ALOX15TDP1LMNA | |
| SCHEMBL3722699 | 0.81 | ALDH1A1 (0.45) | ALDH1A1ALOX15LMNAMAPTSMN1; SMN2 | |
| SCHEMBL29607722 | 0.81 | ALDH1A1 (0.45) | ALDH1A1ALOX15LMNAMAPTSMN1; SMN2 | |
| SCHEMBL3888136 | 0.81 | ALDH1A1 (0.75) | ALDH1A1CYP3A4ALOX15TDP1LMNA | |
| SCHEMBL20298758 | 0.81 | ALDH1A1 (0.49) | ALDH1A1CYP3A4ALOX15TDP1LMNA | |
| SCHEMBL22890463 | 0.80 | ALDH1A1 (0.44) | ALDH1A1CYP3A4ALOX15TDP1LMNA | |
| SCHEMBL1448259 | 0.79 | ALDH1A1 (0.44) | ALDH1A1CYP3A4ALOX15TDP1LMNA | |
| SCHEMBL10770551 | 0.79 | ALDH1A1 (0.67) | ALDH1A1CYP3A4ALOX15TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3994142-A1 | CHEMICAL COMPOUNDS | Borah, Inc. (US) | 2022-05-11 | — | — | EP | disclosed |
| WO-2010133312-A1 | HALOGEN-SUBSTITUTED COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2010-11-25 | — | — | WO | disclosed |