Sugi Predict

Sugi Predict / Compounds / SCHEMBL1740988

SCHEMBL1740988

SCHEMBL1740988

O=C(O)c1cc([N+](=O)[O-])cc(F)c1F

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 5/20 0.46
▸ MAPT P10636 3/20 0.46
▸ TDP1 Q9NUW8 2/20 0.46
▸ CYP3A4 P08684 2/20 0.46
▸ ALOX15 P16050 1/20 0.46
▸ MAPK1 P28482 1/20 0.45
▸ TP53 P04637 2/20 0.43
▸ HTT P42858 1/20 0.43
▸ CTSV O60911 1/20 0.43
▸ CTSL P07711 1/20 0.43
▸ CA1 P00915 1/20 0.42
▸ CA2 P00918 1/20 0.42
▸ KMT2A Q03164 3/20 0.42
▸ SMN1; SMN2 Q16637 2/20 0.42
▸ DTYMK P23919 1/20 0.41
▸ LMNA P02545 1/20 0.41
▸ MEN1 O00255 2/20 0.40
▸ POLB P06746 1/20 0.40
▸ CASP6 P55212 1/20 0.40
▸ GAA P10253 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7458202 0.85 ALDH1A1 (0.44) ALDH1A1MAPTTDP1CYP3A4ALOX15
SCHEMBL20298758 0.84 ALDH1A1 (0.49) ALDH1A1MAPTTDP1CYP3A4ALOX15
SCHEMBL5219288 0.84 CA1 (0.53) ALDH1A1MAPTTDP1CYP3A4ALOX15
SCHEMBL1978032 0.84 MAPT (0.46) ALDH1A1MAPTTDP1CYP3A4ALOX15
SCHEMBL24723042 0.82 ALDH1A1 (0.47) ALDH1A1MAPTTDP1CYP3A4ALOX15
SCHEMBL12931078 0.82 ALDH1A1 (0.50) ALDH1A1MAPTTDP1CYP3A4ALOX15
SCHEMBL1099320 0.82 ALDH1A1 (0.47) ALDH1A1MAPTTDP1CYP3A4ALOX15
SCHEMBL3723504 0.82 ALDH1A1 (0.51) ALDH1A1MAPTTDP1CYP3A4ALOX15
SCHEMBL22032848 0.82 ALDH1A1 (0.46) ALDH1A1MAPTTDP1CYP3A4ALOX15
SCHEMBL1448259 0.82 ALDH1A1 (0.44) ALDH1A1MAPTTDP1CYP3A4ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118621569-A Polyvinyl alcohol fiber surface acetalation modification method 海南大学 2024-09-10 — — CN claimed
EP-4644362-A1 CYCLOPROPYLAMIDE COMPOUNDS AGAINST PARASITES IN FISH Intervet International B.V. (NL) 2025-11-05 — — EP disclosed
CN-118621569-A Polyvinyl alcohol fiber surface acetalation modification method 海南大学 2024-09-10 — — CN disclosed
WO-2024125629-A1 UREIC COMPOUND AND PHARMACEUTICAL USE THEREOF AS STING INHIBITOR 中国药科大学 2024-06-20 — — WO disclosed
CN-118044519-A Molecules having pesticidal utility, and intermediates, compositions and methods related thereto 科迪华农业科技有限责任公司 2024-05-17 — — CN disclosed
US-20240116854-A1 CYCLOPROPYLAMIDE COMPOUNDS AGAINST PARASITES IN FISH INTERVET INC. (US) 2024-04-11 — — US disclosed
CN-117756698-A Urea compound and medical application thereof as STING inhibitor 中国药科大学 2024-03-26 — — CN disclosed
CN-110072842-B Molecules having pesticidal utility, and intermediates, compositions and methods related thereto 科迪华农业科技有限责任公司 2024-02-02 — — CN disclosed
CN-117241669-A Cyclopropylamide compounds against parasites in fish 英特威国际有限公司荷兰疫苗厂 2023-12-15 — — CN disclosed
EP-4284174-A1 CYCLOPROPYLAMIDE COMPOUNDS AGAINST PARASITES IN FISH Intervet International B.V. (NL) 2023-12-06 — — EP disclosed
US-20100204208-A1 PROTEIN KINASE C INHIBITORS AND USES THEREOF MIDCAP FINANCIAL TRUST 2010-08-12 — — US disclosed
US-20100204208-A1 PROTEIN KINASE C INHIBITORS AND USES THEREOF MIDCAP FINANCIAL TRUST 2010-08-12 — — US disclosed
EP-1968948-A2 NOVEL HYDROGEN SULFATE SALT Array Biopharma, Inc. (US) 2008-09-17 — — EP disclosed
WO-2007076245-A2 NOVEL HYDROGEN SULFATE SALT ARRAY BIOPHARMA INC. (US) 2007-07-05 — — WO disclosed
EP-1797042-A1 INDOZOLONE DERIVATIVES AS 11B-HSD1 INHIBITORS F.HOFFMANN-LA ROCHE AG (CH) 2007-06-20 — — EP disclosed
WO-2006034804-A1 INDOZOLONE DERIVATIVES AS 11B-HSD1 INHIBITORS F.HOFFMANN-LA ROCHE AG (CH) 2006-04-06 — — WO disclosed
EP-1177193-A1 PROCESS FOR THE PREPARATION OF 6-(PERFLUOROALKYL)URACIL COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 2002-02-06 — — EP disclosed
EP-1169308-A1 PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF 1,3-OXAZIN-6-ONES AND URACILS BASF AKTIENGESELLSCHAFT (DE) 2002-01-09 — — EP disclosed
WO-2000049002-A1 PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF 1,3-OXAZIN-6-ONES AND URACILS AMERICAN CYANAMID COMPANY (US) 2000-08-24 — — WO disclosed
WO-2000049016-A1 PROCESS FOR THE PREPARATION OF 6-(PERFLUOROALKYL)URACIL COMPOUNDS AMERICAN CYANAMID COMPANY (US) 2000-08-24 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100204208-A1 PROTEIN KINASE C INHIBITORS AND USES THEREOF PRKCH, PRKCA, PRKCB ALDH1A1 4361/4885MAPT 2530/4885TDP1 754/4885
US-20240116854-A1 CYCLOPROPYLAMIDE COMPOUNDS AGAINST PARASITES IN FISH PIGO, PPIA, PPT1 ALDH1A1 623/4885MAPT 4295/4885TDP1 3608/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.