Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 3/20 | 0.58 |
| ▸ | DEGS1 | O15121 | 14/20 | 0.49 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3535964 | 0.80 | DEGS1 (0.50) | HCAR3DEGS1 | |
| SCHEMBL3535967 | 0.80 | DEGS1 (0.50) | HCAR3DEGS1 | |
| SCHEMBL6921057 | 0.77 | HCAR3 (0.55) | HCAR3 | |
| SCHEMBL19023405 | 0.76 | — | — | |
| SCHEMBL13249613 | 0.75 | HCAR3 (0.53) | HCAR3PDE10A | |
| SCHEMBL20350367 | 0.75 | HCAR3 (0.53) | HCAR3PDE10A | |
| SCHEMBL12243807 | 0.75 | HCAR3 (0.53) | HCAR3DEGS1PDE10A | |
| SCHEMBL8002428 | 0.75 | FDPS (0.56) | HCAR3 | |
| SCHEMBL4476961 | 0.75 | HCAR3 (0.53) | HCAR3PDE10A | |
| SCHEMBL29581129 | 0.75 | HCAR3 (0.53) | HCAR3PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |