Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3724011 | 0.83 | GAA (0.33) | GAAHTR2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL3024862 | 0.77 | CA1 (0.39) | HTR2C | |
| SCHEMBL3016030 | 0.69 | KCNH2 (0.36) | — | |
| SCHEMBL3724329 | 0.69 | KDM4C (0.31) | — | |
| SCHEMBL3723353 | 0.68 | CYP1A2 (0.42) | ALDH1A1 | |
| SCHEMBL3020288 | 0.68 | RIPK1 (0.36) | HTR2CMAPK1 | |
| SCHEMBL3016282 | 0.65 | — | — | |
| SCHEMBL3023008 | 0.64 | HTR2C (0.32) | HTR2C | |
| SCHEMBL1149585 | 0.60 | GAA (0.51) | GAAHTR2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL334990 | 0.60 | OPRL1 (0.41) | HTR2AHTR2CHTR2BOPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2139898-A1 | COMPOUNDS | Glaxo Group Limited (GB) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008128961-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2008-10-30 | — | — | WO | disclosed |