Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.36 |
| ▸ | ACACA | Q13085 | 1/20 | 0.36 |
| ▸ | NQO1 | P15559 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.34 |
| ▸ | SCN7A | Q01118 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3727054 | 0.76 | ACACB (0.61) | ACACBACACA | |
| SCHEMBL4516981 | 0.76 | SMN1; SMN2 (0.37) | ACACBACACACYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL3728872 | 0.75 | ACACB (0.49) | ACACBACACAALOX5 | |
| SCHEMBL3796408 | 0.75 | ADRA2A (0.51) | ACACBACACASCN9APDE3BPDE3A | |
| SCHEMBL3720041 | 0.75 | MAP4K4 (0.48) | SCN9ASCN7AKCNH2MAP4K4 | |
| SCHEMBL10914905 | 0.75 | BACE1 (0.37) | NQO1SCN9ASCN7AKCNH2TP53 | |
| SCHEMBL3797164 | 0.75 | ACACB (0.33) | ACACBACACAALOX5PDE3BPDE3A | |
| SCHEMBL3720735 | 0.75 | ACACB (0.48) | ACACBACACASCN9AALOX5 | |
| SCHEMBL3722662 | 0.74 | ACACB (0.47) | ACACBACACASCN9AALOX5 | |
| SCHEMBL13076818 | 0.74 | ACACB (0.43) | ACACBACACASCN9AALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |