Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRA | P11474 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 8/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 5/20 | 0.42 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3727616 | 0.92 | ESRRA (0.52) | ESRRAMAPTMEN1HTTKMT2A | |
| SCHEMBL2715191 | 0.86 | MRGPRX4 (0.53) | ESRRAMAPTMEN1HTTKMT2A | |
| SCHEMBL3719884 | 0.81 | ESRRA (0.51) | ESRRAMAPTMEN1KMT2ANPSR1 | |
| SCHEMBL3720850 | 0.79 | PPARA (0.43) | MAPTPPARAALDH1A1PPARGKDM4E | |
| SCHEMBL3720848 | 0.79 | CYP17A1 (0.46) | CYP2C9 | |
| SCHEMBL3726992 | 0.79 | ESRRA (0.53) | ESRRAMAPTHTTKMT2AADRB2 | |
| SCHEMBL3724597 | 0.79 | PPARA (0.41) | ESRRAMAPTMEN1HTTKMT2A | |
| SCHEMBL3725192 | 0.77 | ESRRA (0.56) | ESRRAMAPTMEN1HTTKMT2A | |
| SCHEMBL3724477 | 0.77 | PPARA (0.42) | MAPTMEN1HTTKMT2ANPSR1 | |
| SCHEMBL15352043 | 0.77 | MRGPRX4 (0.52) | ESRRAMAPTMEN1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |