Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRA | P11474 | 1/20 | 0.53 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.48 |
| ▸ | ACACB | O00763 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.45 |
| ▸ | PARG | Q86W56 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3727616 | 0.85 | ESRRA (0.52) | ESRRAALDH1A1GAAMAPTL3MBTL1 | |
| SCHEMBL3725192 | 0.85 | ESRRA (0.56) | ESRRAALDH1A1GAAMAPTL3MBTL1 | |
| SCHEMBL3723786 | 0.85 | ACACB (0.48) | ESRRACREBBPACACBALDH1A1GAA | |
| SCHEMBL15763863 | 0.85 | CREBBP (0.54) | CREBBPALDH1A1GAAL3MBTL1MAPK1 | |
| SCHEMBL3726759 | 0.83 | CREBBP (0.43) | ESRRACREBBPALDH1A1GAAMAPT | |
| SCHEMBL3719330 | 0.83 | ESRRA (0.60) | ESRRAALDH1A1GAAMAPTL3MBTL1 | |
| SCHEMBL3719235 | 0.82 | MEN1 (0.58) | ESRRAALDH1A1GAAMAPTPARG | |
| SCHEMBL3719884 | 0.81 | ESRRA (0.51) | ESRRAALDH1A1GAAMAPTL3MBTL1 | |
| SCHEMBL3720205 | 0.81 | ESRRA (0.52) | ESRRAALDH1A1GAAMAPTPARG | |
| SCHEMBL3721612 | 0.80 | PDE4B (0.52) | ESRRACREBBPACACBALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |