Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 14/20 | 0.42 |
| ▸ | PPARG | P37231 | 5/20 | 0.39 |
| ▸ | PPARD | Q03181 | 8/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3727617 | 0.92 | PPARA (0.44) | PPARAPPARGPPARDFFAR1MEN1 | |
| SCHEMBL3720490 | 0.83 | GLA (0.48) | PPARAPPARGFFAR1SMN1; SMN2 | |
| SCHEMBL3719886 | 0.81 | TTR (0.42) | PPARAPPARGPPARDMEN1MAPT | |
| SCHEMBL3720850 | 0.78 | PPARA (0.43) | PPARAPPARGMAPTALDH1A1MAPK1 | |
| SCHEMBL3726994 | 0.78 | ACACB (0.42) | FFAR1MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL3724474 | 0.77 | ESRRA (0.47) | PPARAPPARGPPARDMEN1MAPT | |
| SCHEMBL3720208 | 0.77 | FFAR1 (0.39) | PPARAPPARGPPARDFFAR1 | |
| SCHEMBL3728680 | 0.76 | RAB9A (0.45) | PPARGFFAR1MEN1MAPTHTT | |
| SCHEMBL3722769 | 0.75 | CA2 (0.41) | — | |
| SCHEMBL3720487 | 0.75 | HTT (0.41) | PPARAPPARGMEN1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |