Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 4/20 | 0.42 |
| ▸ | SUZ12 | Q15022 | 4/20 | 0.42 |
| ▸ | EZH2 | Q15910 | 4/20 | 0.42 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 5/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | HBB | P68871 | 1/20 | 0.32 |
| ▸ | STAT6 | P42226 | 2/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.31 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10291388 | 0.79 | EED (0.40) | EEDSUZ12EZH2TRPV3STAT6 | |
| SCHEMBL10009384 | 0.78 | FFAR1 (0.45) | EEDSUZ12EZH2 | |
| SCHEMBL1707989 | 0.76 | EED (0.38) | EEDSUZ12EZH2TRPV3GAA | |
| SCHEMBL1708457 | 0.72 | STAT6 (0.37) | EEDSUZ12EZH2TRPV3GAA | |
| SCHEMBL1708456 | 0.72 | FFAR1 (0.45) | STAT6 | |
| SCHEMBL3722112 | 0.72 | MAPT (0.43) | GAAMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL1707869 | 0.71 | STAT6 (0.36) | EEDSUZ12EZH2TRPV3GAA | |
| SCHEMBL1707868 | 0.71 | FFAR1 (0.38) | EEDSUZ12EZH2TRPV3GAA | |
| SCHEMBL13046563 | 0.71 | FFAR1 (0.40) | GAASTAT6MTORALOX15MAPK1 | |
| SCHEMBL1708222 | 0.69 | STAT6 (0.36) | EEDSUZ12EZH2TRPV3GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010143733-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-12-16 | — | — | WO | disclosed |