Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT6 | P42226 | 6/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAF1 | P04049 | 6/20 | 0.34 |
| ▸ | BRAF | P15056 | 6/20 | 0.34 |
| ▸ | BDKRB1 | P46663 | 3/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | EED | O75530 | 1/20 | 0.33 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.33 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.33 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1707989 | 0.94 | EED (0.38) | STAT6GAAALOX15MAPK1RAF1 | |
| SCHEMBL1708599 | 0.88 | WNT3A (0.38) | RAF1BRAFMTORAOC3EED | |
| SCHEMBL1708457 | 0.88 | STAT6 (0.37) | STAT6GAAALOX15MAPK1RAF1 | |
| SCHEMBL1707869 | 0.87 | STAT6 (0.36) | STAT6GAAALOX15MAPK1RAF1 | |
| SCHEMBL1707923 | 0.83 | GAA (0.36) | STAT6GAAALOX15MAPK1RAF1 | |
| SCHEMBL13046563 | 0.81 | FFAR1 (0.40) | STAT6GAAALOX15MAPK1BDKRB1 | |
| SCHEMBL1708456 | 0.81 | FFAR1 (0.45) | STAT6 | |
| SCHEMBL1708224 | 0.81 | GAA (0.36) | STAT6GAAALOX15MAPK1RAF1 | |
| SCHEMBL1708225 | 0.80 | KLKB1 (0.35) | GAAMTOREZH2 | |
| SCHEMBL1707868 | 0.80 | FFAR1 (0.38) | STAT6GAAALOX15MAPK1RAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440541-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2012-04-18 | — | — | EP | disclosed |
| WO-2010143733-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-12-16 | — | — | WO | disclosed |