Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT6 | P42226 | 6/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | EED | O75530 | 1/20 | 0.34 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.34 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.34 |
| ▸ | RAF1 | P04049 | 5/20 | 0.34 |
| ▸ | BRAF | P15056 | 5/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.33 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1708457 | 0.99 | STAT6 (0.37) | STAT6GAAALOX15MAPK1EED | |
| SCHEMBL1708224 | 0.92 | GAA (0.36) | STAT6GAAALOX15MAPK1RAF1 | |
| SCHEMBL3719582 | 0.87 | WNT3A (0.39) | GAAALOX15MAPK1EEDSUZ12 | |
| SCHEMBL13046563 | 0.87 | FFAR1 (0.40) | STAT6GAAALOX15MAPK1MTOR | |
| SCHEMBL1708222 | 0.87 | STAT6 (0.36) | STAT6GAAALOX15MAPK1EED | |
| SCHEMBL1708456 | 0.87 | FFAR1 (0.45) | STAT6FFAR1 | |
| SCHEMBL1707868 | 0.85 | FFAR1 (0.38) | STAT6GAAALOX15MAPK1EED | |
| SCHEMBL1707901 | 0.83 | GAA (0.38) | STAT6GAAALOX15MAPK1RAF1 | |
| SCHEMBL13046578 | 0.80 | FFAR1 (0.40) | STAT6GAAALOX15MAPK1EED | |
| SCHEMBL1707989 | 0.80 | EED (0.38) | STAT6GAAALOX15MAPK1EED |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440541-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2012-04-18 | — | — | EP | disclosed |
| WO-2010143733-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-12-16 | — | — | WO | disclosed |