Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.38 |
| ▸ | FDPS | P14324 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL114337 | 0.79 | ALOX15 (0.55) | ALOX15ALDH1A1TSHRUSP2TDP1 | |
| SCHEMBL13279733 | 0.79 | ALOX15 (0.55) | ALOX15ALDH1A1TSHRUSP2TDP1 | |
| SCHEMBL18316483 | 0.79 | ALOX15 (0.55) | ALOX15ALDH1A1TSHRUSP2TDP1 | |
| SCHEMBL19296596 | 0.79 | ALOX15 (0.55) | ALOX15ALDH1A1TSHRUSP2TDP1 | |
| SCHEMBL27639593 | 0.79 | ALOX15 (0.55) | ALOX15ALDH1A1TSHRUSP2TDP1 | |
| SCHEMBL7134301 | 0.76 | ALOX15 (0.57) | ALOX15ALDH1A1TSHRUSP2TDP1 | |
| SCHEMBL877393 | 0.76 | ALOX15 (0.57) | ALOX15ALDH1A1TSHRUSP2TDP1 | |
| SCHEMBL9359140 | 0.75 | ALOX15 (0.50) | ALOX15ALDH1A1TSHRUSP2TDP1 | |
| SCHEMBL3696800 | 0.74 | ALOX15 (0.58) | ALOX15ALDH1A1TSHRUSP2TDP1 | |
| SCHEMBL15457016 | 0.74 | ALOX15 (0.59) | ALOX15ALDH1A1TSHRUSP2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10800790-B2 | Sesquiterpenoid STAT3 inhibitors | UNIVERSITY OF HAWAII (US) | 2020-10-13 | — | — | US | claimed |
| JP-62019550-A | — | — | None | — | — | JP | disclosed |
| US-7858349-B2 | Anti-cancer compounds | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2010-12-28 | — | — | US | disclosed |
| WO-2010127381-A1 | DIAGNOSIS, MONITORING, PROGNOSIS, PREVENTION AND TREATMENT OF ANEURYSMS | JAMES COOK UNIVERSITY (AU) | 2010-11-11 | — | — | WO | disclosed |
| US-20090088454-A1 | ANTI-CANCER COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2009-04-02 | — | — | US | disclosed |
| US-7427496-B2 | Anti-cancer compounds | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2008-09-23 | — | — | US | disclosed |
| US-20060183772-A1 | To inhibit tumor growth in an animal; to induce apoptosis | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2006-08-17 | — | — | US | disclosed |
| US-7071359-B1 | Neuropathy improvers containing nitrogenous compounds as the active ingredient | TEIJIN LIMITED (JP) | 2006-07-04 | — | — | US | disclosed |
| EP-1201235-B1 | NEUROPATHY IMPROVERS CONTAINING NITROGENOUS COMPOUNDS AS THE ACTIVE INGREDIENT | TEIJIN LTD (JP) | 2005-10-12 | — | — | EP | disclosed |
| EP-1201235-A1 | NEUROPATHY IMPROVERS CONTAINING NITROGENOUS COMPOUNDS AS THE ACTIVE INGREDIENT | TEIJIN LIMITED (JP) | 2002-05-02 | — | — | EP | disclosed |
| JP-S6219550-A | PRODUCTION OF MENTHONE | TOYOTAMA KORYO KK | 1987-01-28 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10800790-B2 | Sesquiterpenoid STAT3 inhibitors | STAT3, JAK2, STAT6 | ALOX15 2608/4885ALDH1A1 1903/4885TSHR 3106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.