Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.35 |
| ▸ | FDPS | P14324 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3255346 | 0.84 | ALOX15 (0.62) | ALOX15ALDH1A1TSHRUSP2NFE2L2 | |
| SCHEMBL25666802 | 0.76 | ALOX15 (0.52) | ALOX15ALDH1A1TSHRUSP2NFE2L2 | |
| SCHEMBL3724907 | 0.75 | ALOX15 (0.55) | ALOX15ALDH1A1TSHRUSP2NFE2L2 | |
| SCHEMBL26622167 | 0.74 | — | — | |
| SCHEMBL11866536 | 0.74 | ALOX15 (0.65) | ALOX15ALDH1A1TSHRUSP2NFE2L2 | |
| SCHEMBL28647885 | 0.73 | ALOX15 (0.57) | ALOX15ALDH1A1TSHRUSP2NFE2L2 | |
| SCHEMBL28647883 | 0.73 | ALOX15 (0.57) | ALOX15ALDH1A1TSHRUSP2NFE2L2 | |
| SCHEMBL7134301 | 0.72 | ALOX15 (0.57) | ALOX15ALDH1A1TSHRUSP2NFE2L2 | |
| SCHEMBL877393 | 0.72 | ALOX15 (0.57) | ALOX15ALDH1A1TSHRUSP2NFE2L2 | |
| SCHEMBL6720281 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0449049-B1 | Naphthalenedicarboxylic acid esters | HOFFMANN LA ROCHE (CH) | 1994-12-28 | — | — | EP | disclosed |
| US-5230828-A | NAPHTHALENEDICARBOXYLIC ACID ESTERS | HOFFMANN-LA ROCHE INC. (US) | 1993-07-27 | — | — | US | disclosed |
| EP-0449049-A2 | Naphthalenedicarboxylic acid esters | F. HOFFMANN-LA ROCHE AG (CH) | 1991-10-02 | — | — | EP | disclosed |