Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3000328 | 0.91 | MCL1 (0.35) | NR1H2NR1H3 | |
| SCHEMBL27808381 | 0.84 | NR1H2 (0.36) | NR1H2NR1H3 | |
| SCHEMBL3011389 | 0.84 | NR1H2 (0.46) | NR1H2NR1H3 | |
| SCHEMBL3415067 | 0.78 | ALDH1A1 (0.35) | — | |
| SCHEMBL29205607 | 0.77 | NR1H2 (0.49) | NR1H2NR1H3 | |
| SCHEMBL30182892 | 0.77 | NR1H2 (0.51) | NR1H2NR1H3 | |
| SCHEMBL29205627 | 0.77 | NR1H2 (0.51) | NR1H2NR1H3 | |
| SCHEMBL31022362 | 0.76 | NR1H2 (0.42) | NR1H2NR1H3 | |
| SCHEMBL3760238 | 0.76 | NR1H2 (0.34) | NR1H2NR1H3 | |
| SCHEMBL3003787 | 0.76 | ACHE (0.35) | NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2178870-A1 | INDOLE AND INDAZOLE COMPOUNDS AS AN INHIBITOR OF CELLULAR NECROSIS | LG Life Sciences Ltd. (KR) | 2010-04-28 | — | — | EP | disclosed |
| WO-2009025478-A1 | INDOLE AND INDAZOLE COMPOUNDS AS AN INHIBITOR OF CELLULAR NECROSIS | LG LIFE SCIENCES LTD. (KR) | 2009-02-26 | — | — | WO | disclosed |