Mannitol

Mannitol

SCHEMBL3725317

CC(C)C(N)=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
TDP1 Q9NUW8 2/20 0.52
USP2 O75604 1/20 0.52
SLCO1B1 Q9Y6L6 1/20 0.52
PDE4A P27815 1/20 0.50
KDM4E B2RXH2 2/20 0.44
TOP1 P11387 1/20 0.32
TSHR P16473 1/20 0.32
PAX8 Q06710 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11206594 0.86 LMNA (0.50) LMNAL3MBTL1TDP1USP2SLCO1B1
Mannitol SCHEMBL29235000 0.84 LMNA (0.61) LMNAL3MBTL1TDP1USP2SLCO1B1
Mannitol SCHEMBL1504919 0.84 LMNA (0.69) LMNAL3MBTL1TDP1USP2SLCO1B1
Mannitol SCHEMBL28204430 0.84 LMNA (0.69) LMNAL3MBTL1TDP1USP2SLCO1B1
Mannitol SCHEMBL28023612 0.81 USP2 (0.65) LMNAL3MBTL1TDP1USP2SLCO1B1
SCHEMBL4724595 0.80 PDE4A (0.62) LMNAL3MBTL1TDP1USP2SLCO1B1
SCHEMBL30891962 0.80 PDE4A (0.62) LMNAL3MBTL1TDP1USP2SLCO1B1
SCHEMBL20576207 0.80 PDE4A (0.62) LMNAL3MBTL1TDP1USP2SLCO1B1
SCHEMBL1569332 0.80 PDE4A (0.62) LMNAL3MBTL1TDP1USP2SLCO1B1
SCHEMBL31465077 0.80 PDE4A (0.62) LMNAL3MBTL1TDP1USP2SLCO1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100173793-A1 PEPTIDE / PROTEIN IDENTIFICATION USING PHOTOREACTIVE CARRIERS FOR THE IMMOBILISATION OF THE LIGANDS UNIVERSITY OF WARWICK (GB) 2010-07-08 US disclosed
EP-1926992-A2 PEPTIDE / PROTEIN IDENTIFICATION USING PHOTOREACTIVE CARRIERS FOR THE IMMOBILISATION OF THE LIGANDS THE UNIVERSITY OF WARWICK (GB) 2008-06-04 EP disclosed
WO-2007020453-A2 PEPTIDE / PROTEIN IDENTIFICATION USING PHOTOREACTIVE CARRIERS FOR THE IMMOBILISATION OF THE LIGANDS UNIVERSITY OF WARWICK (GB) 2007-02-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100173793-A1 PEPTIDE / PROTEIN IDENTIFICATION USING PHOTOREACTIVE CARRIERS FOR THE IMMOBILISATION OF THE LIGANDS CLTA, CD40, DNPEP LMNA 4613/4885L3MBTL1 2165/4885TDP1 4475/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.