Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 2/20 | 0.49 |
| ▸ | ACACB | O00763 | 9/20 | 0.47 |
| ▸ | ACACA | Q13085 | 5/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 8/20 | 0.41 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.41 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3724294 | 0.88 | PDE4B (0.55) | PDE4BACACBACACASCN9A | |
| SCHEMBL3721868 | 0.83 | PDE4B (0.48) | PDE4BSCN9A | |
| SCHEMBL3718481 | 0.82 | PDE4B (0.54) | PDE4BSCN9ASCN10AHPGDS | |
| SCHEMBL3719548 | 0.82 | PDE4B (0.48) | PDE4BSCN9A | |
| SCHEMBL3720457 | 0.82 | PDE4B (0.48) | PDE4BACACBACACA | |
| SCHEMBL3717769 | 0.82 | PDE4B (0.48) | PDE4B | |
| SCHEMBL3719630 | 0.81 | ACACB (0.60) | ACACBACACA | |
| SCHEMBL3721089 | 0.80 | PDE4B (0.53) | PDE4BACACBACACASCN9A | |
| SCHEMBL3716835 | 0.80 | PDE4B (0.53) | PDE4BSCN9AHPGDS | |
| SCHEMBL3720015 | 0.79 | PDE4B (0.46) | PDE4BSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |