SCHEMBL372540

SCHEMBL372540

C[Si](C)(C)CC([NH])=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6526896 0.69
SCHEMBL442427 0.69
SCHEMBL2965396 0.69
SCHEMBL8789218 0.67
SCHEMBL28841595 0.65
SCHEMBL14560578 0.65 CES1 (0.38)
Lithium Ion SCHEMBL29046155 0.65
SCHEMBL10984500 0.65
SCHEMBL30730735 0.65 OR51E2 (0.40)
SCHEMBL6675846 0.63 KMT2A (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0589335-A1 N1-Substituted- (1H)-1,2,3-Triazolo (4,5-d) pyrimidines, process for their preparation and their use as antiviral means HOECHST AKTIENGESELLSCHAFT (DE) 1994-03-30 EP claimed
EP-2409782-A1 METHOD FOR REFLECTING INFRARED LIGHT Toyo Aluminium Kabushiki Kaisha (JP) 2012-01-25 EP disclosed
EP-0589335-B1 N1-Substituted- (1H)-1,2,3-Triazolo (4,5-d) pyrimidines, process for their preparation and their use as antiviral means HOECHST AG (DE) 2003-06-18 EP disclosed
US-5457091-A N1-substituted 1H-1,2,3-triazolo[4,5,-D]pyrimidines, a process for their preparation and their use as antiviral agents HOECHST AKTIENGESELLSCHAFT (DE) 1995-10-10 US disclosed
EP-0589335-A1 N1-Substituted- (1H)-1,2,3-Triazolo (4,5-d) pyrimidines, process for their preparation and their use as antiviral means HOECHST AKTIENGESELLSCHAFT (DE) 1994-03-30 EP disclosed
US-4822888-A INTERMEDIATES FOR CEPHALOSPORIN ANTIBIOTICS FUJISAWA PHARMACEUTICAL COMPANY, LIMITED (JP) 1989-04-18 US disclosed
US-4354022-A Process for preparing 3-methylenecepham compounds or a salt thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1982-10-12 US disclosed