SCHEMBL6526896

SCHEMBL6526896

CC(=O)C[Si](C)(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tert-Butylamine SCHEMBL8148552 0.86 ALDH1A1 (0.32)
SCHEMBL28488688 0.79 ALDH1A1 (0.41)
SCHEMBL8330396 0.76 KDM4E (0.44)
SCHEMBL29050923 0.74 ALDH1A1 (0.44)
SCHEMBL14560578 0.73 CES1 (0.38)
SCHEMBL442427 0.71
SCHEMBL5394765 0.69
SCHEMBL14560562 0.69 TSHR (0.32)
SCHEMBL16150019 0.69
SCHEMBL372540 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111218104-B Heat-resistant thermoplastic polyurethane elastomer composition and preparation method and application thereof 万华化学集团股份有限公司 2022-04-22 CN disclosed
EP-3341375-B1 PROCESS FOR PREPARING PARP INHIBITOR, CRYSTALLINE FORMS, AND USES THEREOF BEIGENE LTD (KY) 2022-04-13 EP disclosed
US-20180044580-A1 METHODS OF EXTRACTING HYDROCARBONS FROM SUBTERRANEAN FORMATIONS BAKER HUGHES INC (US) 2018-02-15 US disclosed
US-9816026-B2 Methods of extracting hydrocarbons from subterranean formations Baker Hughes, LLC (US) 2017-11-14 US disclosed
US-20170261874-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, IMAGE FORMING APPARATUS, AND CONDUCTIVE SUBSTRATE THAT MAY BE INCLUDED IN ELECTROPHOTOGRAPHIC PHOTORECEPTOR FUJI XEROX CO., LTD. (JP) 2017-09-14 US disclosed
US-20160348488-A1 METHODS OF EXTRACTING HYDROCARBONS FROM SUBTERRANEAN FORMATIONS BAKER HUGHES INCORPORATED 2016-12-01 US disclosed
US-9273080-B2 Metal complexes MEREK PATENT GMBH (DE) 2016-03-01 US disclosed
WO-2016012333-A1 PESTICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2016-01-28 WO disclosed
WO-2014150132-A1 INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL MERCK SHARP & DOHME CORP. (US) 2014-09-25 WO disclosed
US-20130082209-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2013-04-04 US disclosed
US-20100055416-A1 COMPOSITE AND MANUFACTURING METHOD THEREOF SAMSUNG ELECTRO-MECHANICS CO., LTD. (KR) 2010-03-04 US disclosed
US-6887817-B2 Olefin polymerization catalyst and process for preparing polyolefins using said catalyst FORMOSA PLASTICS CORPORATION, U.S.A. (US) 2005-05-03 US disclosed
US-20040039139-A1 Olefin polymerization catalyst and process for preparing polyolefins using said catalyst FORMOSA PLASTICS CO., U.S.A. 2004-02-26 US disclosed
US-20030069372-A1 Olefin polymerization catalyst and process for preparing polyolefins with said catalyst FORMOSA PLASTICS CORPORATION, U.S.A. 2003-04-10 US disclosed
US-4187385-A TITANIUM COMPONENT COPULVERIZED WITH ORGANOALUMINUM COMPOUND AND ETHYLENE OR A-OLEFINS, PARTICLE SIZE MITSUI TOATSU CHEMICAL, INC. (JP) 1980-02-05 US disclosed