SCHEMBL442427

SCHEMBL442427

C[Si](C)(C)CC(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29779954 0.84 FFAR3 (0.30)
SCHEMBL29065871 0.79 FFAR3 (0.41)
SCHEMBL632284 0.79 FFAR3 (0.41)
SCHEMBL8415864 0.76
SCHEMBL30203760 0.73
SCHEMBL30730735 0.73 OR51E2 (0.40)
SCHEMBL11007102 0.72 LDHA (0.38)
SCHEMBL6526896 0.71
SCHEMBL512417 0.71 FFAR3 (0.35)
SCHEMBL16554200 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 780 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 EP claimed
CN-118791520-A Synthesis method of tri (trimethylsilyl) phosphate 山东阳谷华泰化工股份有限公司 2024-10-18 CN claimed
CN-118146863-B Water-soluble wafer cutting fluid and preparation method thereof 辽宁格物精细化工科技有限公司 2024-09-06 CN claimed
WO-2024167565-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS PURDUE RESEARCH FOUNDATION (US) 2024-08-15 WO claimed
CN-118146863-A Water-soluble wafer cutting fluid and preparation method thereof 辽宁格物精细化工科技有限公司 2024-06-07 CN claimed
CN-116525936-A Electrolyte containing silicon-based lithium salt and preparation method and application thereof 厦门稀土材料研究所 2023-08-01 CN claimed
CN-116022802-A Nonmetal high-entropy compound and preparation method and application thereof 广州大学 2023-04-28 CN claimed
CN-115699259-A Surface treatment method for semiconductor substrate and surface treatment agent composition 中央硝子株式会社 2023-02-03 CN claimed
CN-115458794-A Non-ignition high-energy-density sodium ion/lithium ion solid-state battery and production method thereof 新疆赛创新能源有限公司 2022-12-09 CN claimed
CN-110395939-B Waterproof enhanced alkali-free liquid accelerator and preparation method thereof 科之杰新材料集团有限公司 2022-04-22 CN claimed
US-6042994-A FORMING A NANOPOROUS DIELECTRIC COMPOSITION ON A SUBSTRATE, OPTIONALLY SURFACE MODIFYING IT, OPTIONALLY HEATING TO EVAPORATE SOLVENT, EXPOSING TO ELECTRON BEAM RADIATION, AND OPTIONALLY THERMAL ANNEALING; STRENGTH, SOLVENT RESISTANCE ALLIEDSIGNAL INC. (US) 2000-03-28 US claimed
WO-2000002233-A2 SIMPLIFIED PROCESS FOR PRODUCING NANOPOROUS SILICA ALLIEDSIGNAL INC. (US) 2000-01-13 WO claimed
WO-1999036953-A1 NANOPOROUS SILICA DIELECTRIC FILMS MODIFIED BY ELECTRON BEAM EXPOSURE AND HAVING LOW DIELECTRIC CONSTANT AND LOW WATER CONTENT ALLIEDSIGNAL INC. (US) 1999-07-22 WO claimed
US-5919552-A Coated substrates and methods XEROX CORPORATION (US) 1999-07-06 US claimed
EP-0583338-B1 METHOD FOR SYNTHESIZING PEPTIDES, NOVEL AMINO ACID DERIVATIVES USED THEREIN, AND METHODS FOR PREPARING SAME PROPEPTIDE SA (FR) 1997-03-12 EP claimed
US-5049611-A RTV elastomers DOW CORNING CORPORATION (US) 1991-09-17 US claimed
EP-0291670-B1 VAPOR PHASE PHOTORESIST SILYLATION PROCESS International Business Machines Corporation (US) 1991-02-20 EP claimed
US-4808511-A N,N-DIMETHYLAMINOTRIMETHYLSILANE, TRIMETHYLSILYLACETATE INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1989-02-28 US claimed
EP-0291670-A1 Vapor phase photoresist silylation process International Business Machines Corporation (US) 1988-11-23 EP claimed
US-4282145-A Process for the preparation of azetidines GIST-BROCADES N.V. (NL) 1981-08-04 US claimed