Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3R1 | P27986 | 19/20 | 0.74 |
| ▸ | PIK3CA | P42336 | 19/20 | 0.74 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL633416 | 0.89 | PIK3CA (0.74) | PIK3R1PIK3CAPIK3CDKCNH2 | |
| SCHEMBL15603073 | 0.86 | PIK3R1 (0.77) | PIK3R1PIK3CAPIK3CDKCNH2 | |
| SCHEMBL3725366 | 0.86 | PIK3CA (0.55) | PIK3R1PIK3CAPIK3CDKCNH2 | |
| SCHEMBL5562537 | 0.85 | PIK3R1 (1.00) | PIK3R1PIK3CAPIK3CDKCNH2 | |
| SCHEMBL632497 | 0.79 | PIK3R1 (0.74) | PIK3R1PIK3CAPIK3CD | |
| SCHEMBL631666 | 0.79 | PIK3R1 (0.62) | PIK3R1PIK3CAPIK3CD | |
| SCHEMBL632841 | 0.77 | PIK3R1 (0.72) | PIK3R1PIK3CAPIK3CD | |
| SCHEMBL893447 | 0.76 | PIK3CA (0.71) | PIK3R1PIK3CAPIK3CD | |
| SCHEMBL633055 | 0.76 | PIK3R1 (0.53) | PIK3R1PIK3CAPIK3CD | |
| SCHEMBL2724529 | 0.76 | PIK3R1 (0.54) | PIK3R1PIK3CAPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010119264-A1 | IMIDAZOPYRAZINES FOR USE AS KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCÓLOGICAS (CNIO) (ES) | 2010-10-21 | — | — | WO | disclosed |