SCHEMBL3725516

SCHEMBL3725516

O=[C]/C(=C\c1ccccc1)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C1 Q04828 1/20 0.50
ALDH1A1 P00352 6/20 0.46
MAPT P10636 6/20 0.46
RAB9A P51151 5/20 0.46
MAPK1 P28482 3/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
PRMT1 Q99873 1/20 0.46
LMNA P02545 3/20 0.43
KDM4E B2RXH2 2/20 0.43
HPGD P15428 2/20 0.43
POLB P06746 2/20 0.43
MEN1 O00255 1/20 0.43
HTT P42858 1/20 0.43
KMT2A Q03164 1/20 0.43
NPC1 O15118 4/20 0.42
TSHR P16473 1/20 0.42
AKR1C3 P42330 1/20 0.42
ESR1 P03372 1/20 0.41
PLIN1 O60240 1/20 0.41
BCHE P06276 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2119744 1.00 AKR1C1 (0.50) AKR1C1ALDH1A1MAPTRAB9AMAPK1
SCHEMBL2119746 1.00 AKR1C1 (0.50) AKR1C1ALDH1A1MAPTRAB9AMAPK1
SCHEMBL27501942 0.82 CYP11B2 (0.54) ALDH1A1MAPTRAB9AMAPK1LMNA
SCHEMBL247445 0.78 RAB9A (0.69) AKR1C1ALDH1A1MAPTRAB9AMAPK1
SCHEMBL247444 0.78 RAB9A (0.69) AKR1C1ALDH1A1MAPTRAB9AMAPK1
SCHEMBL347800 0.78 RAB9A (0.69) AKR1C1ALDH1A1MAPTRAB9AMAPK1
SCHEMBL11474267 0.77 TDP1 (0.42) ALDH1A1MAPTMAPK1L3MBTL1LMNA
SCHEMBL262667 0.77 CES1 (0.40) ALDH1A1MAPTRAB9AMAPK1L3MBTL1
SCHEMBL262668 0.77 CES1 (0.40) ALDH1A1MAPTRAB9AMAPK1L3MBTL1
SCHEMBL145087 0.77 CES1 (0.40) ALDH1A1MAPTRAB9AMAPK1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112470046-A Retardation film and method for producing same 林特琅普股份有限公司 2021-03-09 CN claimed
JP-55031851-A None JP disclosed
CN-113474691-A Optical layered body and method for producing same 林特琅普股份有限公司 2021-10-01 CN disclosed
CN-112470046-A Retardation film and method for producing same 林特琅普股份有限公司 2021-03-09 CN disclosed
US-8902398-B2 Optical film laminate, method for producing the same, and liquid crystal display panel using the same HAYASHI ENGINEERING INC. (JP) 2014-12-02 US disclosed
US-20120314159-A1 OPTICAL FILM LAMINATE, METHOD FOR PRODUCING THE SAME, AND LIQUID CRYSTAL DISPLAY PANEL USING THE SAME HAYASHI ENGINEERING INC. (JP) 2012-12-13 US disclosed
US-7858349-B2 Anti-cancer compounds THE REGENTS OF THE UNIVERSITY OF COLORADO (US) 2010-12-28 US disclosed
WO-2010127381-A1 DIAGNOSIS, MONITORING, PROGNOSIS, PREVENTION AND TREATMENT OF ANEURYSMS JAMES COOK UNIVERSITY (AU) 2010-11-11 WO disclosed
WO-2009131274-A1 SYNTHESIS OF PHOTOINITIATOR FREE REACTIVE MESOGENS BASED ON TRIPHENYLENE KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2009-10-29 WO disclosed
WO-2009131274-A1 SYNTHESIS OF PHOTOINITIATOR FREE REACTIVE MESOGENS BASED ON TRIPHENYLENE KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2009-10-29 WO disclosed
US-20090088454-A1 ANTI-CANCER COMPOUNDS THE REGENTS OF THE UNIVERSITY OF COLORADO (US) 2009-04-02 US disclosed
US-7427496-B2 Anti-cancer compounds THE REGENTS OF THE UNIVERSITY OF COLORADO (US) 2008-09-23 US disclosed
US-20060183772-A1 To inhibit tumor growth in an animal; to induce apoptosis NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2006-08-17 US disclosed
JP-2004258426-A BIREFRINGENCE INDUCING MATERIAL AND RETARDATION FILM HAYASHI TELEMPU CO LTD 2004-09-16 JP disclosed
JP-S5531851-A FLAME-RETARDANT RESIN COMPOSITION FUJITSU LTD 1980-03-06 JP disclosed