SCHEMBL3725629

SCHEMBL3725629

CN(C)C(=Cc1ccccc1)C1=CC(=C(C#N)C#N)C=C(C(C)(C)C)O1

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.33
MAPT P10636 3/20 0.33
MAPK1 P28482 2/20 0.33
RAB9A P51151 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
NPC1 O15118 1/20 0.31
MCL1 Q07820 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1462636 0.90 ALDH1A1 (0.37) ALDH1A1MAPTMAPK1RAB9AL3MBTL1
SCHEMBL990257 0.88 ALDH1A1 (0.32) ALDH1A1MAPTMAPK1RAB9AL3MBTL1
SCHEMBL74731 0.85 ALDH1A1 (0.34) ALDH1A1MAPTMAPK1RAB9AL3MBTL1
SCHEMBL28980724 0.85 ALDH1A1 (0.34) ALDH1A1MAPTMAPK1RAB9AL3MBTL1
Iodide SCHEMBL29042229 0.84 ALDH1A1 (0.33) ALDH1A1MAPTMAPK1RAB9AL3MBTL1
Coumarin SCHEMBL1049521 0.73 CA12 (0.37) ALDH1A1MAPTRAB9ANPC1MCL1
SCHEMBL6324930 0.70 ALDH1A1 (0.35) ALDH1A1
Camphor SCHEMBL27923522 0.70 ALDH1A1 (0.37) ALDH1A1MAPTMEN1KMT2A
SCHEMBL28429867 0.69
SCHEMBL7191140 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7719183-B2 Manufacturing method of organic electroluminescent device and an organic electroluminescent device TOPPAN PRINTING CO., LTD. (JP) 2010-05-18 US disclosed
US-7524991-B2 Organic electroluminescent devices, aminostyrylnaphthalene compounds and synthesis intermediates thereof, and production processes of the same SONY CORPORATION (JP) 2009-04-28 US disclosed
US-7402344-B2 Organic electroluminescent devices and aminostyrylnaphthalene compounds SONY CORPORATION (JP) 2008-07-22 US disclosed
US-20080051607-A1 ORGANIC ELECTROLUMINESCENT DEVICES, AMINOSTYRLNAPHTHALENE COMPOUNDS AND SYNTHESIS INTERMEDIATES THEREOF, AND PRODUCTION PROCESSES OF THE SAME SONY CORPORATION (JP) 2008-02-28 US disclosed
US-20070001589-A1 Manufacturing method of organic electroluminescent device and an organic electroluminescent device TOPPAN PRINTING CO., LTD. (JP) 2007-01-04 US disclosed
US-20040265627-A1 Organic electroluminescent devices, aminostyrylnaphthalene compound and synthesis intermediates thereof, and production processes of the same JDI DESIGN AND DEVELOPMENT G.K. (JP) 2004-12-30 US disclosed
EP-1473349-A2 Organic electroluminescent devices, aminostyrylnaphthalene compounds and synthesis intermediates thereof, and production processes of the same SONY CORPORATION (JP) 2004-11-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080051607-A1 ORGANIC ELECTROLUMINESCENT DEVICES, AMINOSTYRLNAPHTHALENE COMPOUNDS AND SYNTHESIS INTERMEDIATES THEREOF, AND PRODUCTION PROCESSES OF THE SAME ASNS, RPS24, L1CAM ALDH1A1 798/4885MAPT 2930/4885MAPK1 2435/4885
US-20040265627-A1 Organic electroluminescent devices, aminostyrylnaphthalene compound and synthesis intermediates thereof, and production processes of the same RPS24, RPL24, CHRND ALDH1A1 328/4885MAPT 2650/4885MAPK1 1810/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.