Nocardamine

Nocardamine

SCHEMBL3725976

O=C1CCC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCN1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 1.00
GAA P10253 1/20 1.00
POLB P06746 1/20 1.00
CRBN Q96SW2 2/20 0.50
FKBP5 Q13451 1/20 0.50
OR51E2 Q9H255 1/20 0.46
CDA P32320 2/20 0.33
CHRM2 P08172 1/20 0.32
CHRM4 P08173 1/20 0.32
CHRM5 P08912 1/20 0.32
CHRM1 P11229 1/20 0.32
CHRM3 P20309 1/20 0.32
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32666021 1.00 KDM4E (1.00) KDM4EGAAPOLBCRBNFKBP5
SCHEMBL32666023 1.00 KDM4E (1.00) KDM4EGAAPOLBCRBNFKBP5
SCHEMBL32666027 1.00 KDM4E (1.00) KDM4EGAAPOLBCRBNFKBP5
Desmethylenylnocardamine SCHEMBL32666030 1.00 KDM4E (1.00) KDM4EGAAPOLBCRBNFKBP5
Dehydroxynocardamine SCHEMBL31483973 1.00 KDM4E (1.00) KDM4EGAAPOLBCRBNFKBP5
SCHEMBL10574088 1.00 KDM4E (1.00) KDM4EGAAPOLBCRBNFKBP5
Nocardamine SCHEMBL28160236 0.98 KDM4E (0.96) KDM4EGAAPOLBCRBNFKBP5
SCHEMBL29855407 0.98 KDM4E (0.96) KDM4EGAAPOLBCRBNFKBP5
SCHEMBL32666026 0.98 KDM4E (0.96) KDM4EGAAPOLBCRBNFKBP5
SCHEMBL26818280 0.93 KDM4E (0.87) KDM4EGAAPOLBCRBNFKBP5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4329709-B1 COMPOSITION COMPRISING DESFERRIOXAMINES AND UV LIGHT FILTER EVONIK OPERATIONS GMBH (DE) 2026-01-28 EP claimed
EP-4637737-A1 COMPOSITIONS CONTAINING BIOSURFACTANTS AND DESFERRIOXAMINES Evonik Operations GmbH (DE) 2025-10-29 EP claimed
EP-4626393-A1 COMPOSITION COMPRISING DESFERRIOXAMINES AND A MIXTURE OF TRIGLYCERIDES Evonik Dr. Straetmans GmbH (DE) 2025-10-08 EP claimed
US-12365945-B2 Urinary microbiomic profiling Convergent Genomics, Inc. (US) 2025-07-22 US claimed
US-20250009891-A1 CONJUGATES OF MONOCYCLIC BETA-LACTAMS AND SIDEROPHORE MIMETICS UNIVERSITY OF NOTRE DAME DU LAC 2025-01-09 US claimed
US-20240207153-A1 DESFERRIOXAMINES AND COMPOSITION CONTAINING UV LIGHT PROTECTION FILTERS EVONIK DR. STRAETMANS GMBH (DE) 2024-06-27 US claimed
WO-2024132679-A1 COMPOSITIONS CONTAINING BIOSURFACTANTS AND DESFERRIOXAMINES EVONIK DR. STRAETMANS GMBH (DE) 2024-06-27 WO claimed
WO-2024115214-A1 COMPOSITION COMPRISING DESFERRIOXAMINES AND A MIXTURE OF TRIGLYCERIDES EVONIK DR. STRAETMANS GMBH (DE) 2024-06-06 WO claimed
EP-4329709-A1 DESFERRIOXAMINES AND COMPOSITION CONTAINING UV LIGHT PROTECTION FILTERS Evonik Dr. Straetmans GmbH (DE) 2024-03-06 EP claimed
EP-3775302-B1 RECOVERY OF METALS FROM INDUSTRIAL WASTEWATER OF LOW METAL CONCENTRATION HELMHOLTZ ZENTRUM DRESDEN (DE) 2023-08-30 EP claimed
EP-3236970-B1 NEW METAL COMPLEXES OF NOCARDAMINE AND THEIR USE IN PHARMACEUTICAL COMPOSITIONS CHEVION MORDECHAI (IL) 2020-12-16 EP claimed
CN-107206091-A New complexes of nocardamine and their use in pharmaceutical compositions 莫迪凯·舍维龙 2017-09-26 CN claimed
EP-2129762-B2 SIDEROPHORE-METAL- COMPLEXES USED AS BLEACH CATALYSTS HENKEL AG & CO KGAA (DE) 2015-10-07 EP claimed
CN-103642723-B Streptomyces and method for preparing two antibiotics by utilizing same JIANGXI NORMAL UNIVERSITY (CN) 2015-09-09 CN claimed
CN-103642723-A Streptomyces and method for preparing two antibiotics by utilizing same UNIV JIANGXI NORMAL 2014-03-19 CN claimed
CN-102657644-B Use of nocardamine in preparation of senile dementia-resisting drug UNIV JIANGXI AGRICULTURAL 2013-12-18 CN claimed
EP-2129762-B1 SIDEROPHORE-METAL- COMPLEXES USED AS BLEACH CATALYSTS HENKEL AG & CO KGAA (DE) 2012-06-27 EP claimed
WO-2010094587-A1 MICROBIAL SIDEROPHORE SYNTHESIS HENKEL AG & CO. KGAA (DE) 2010-08-26 WO claimed
EP-2129762-A1 SIDEROPHORE-METAL- COMPLEXES USED AS BLEACH CATALYSTS Henkel AG & Co. KGaA (DE) 2009-12-09 EP claimed
WO-2008101909-A1 SIDEROPHORE-METAL- COMPLEXES USED AS BLEACH CATALYSTS HENKEL AG & CO. KGAA (DE) 2008-08-28 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250009891-A1 CONJUGATES OF MONOCYCLIC BETA-LACTAMS AND SIDEROPHORE MIMETICS MGAM, OPRM1, BPGM KDM4E 1593/4885GAA 210/4885POLB 510/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.