Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 6/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | S100A4 | P26447 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15691696 | 0.90 | THRB (0.57) | THRBTDP1APEX1KIF11KMT2A | |
| SCHEMBL17729938 | 0.87 | THRB (0.47) | THRBTDP1APEX1PDK2 | |
| SCHEMBL17742236 | 0.86 | THRB (0.53) | THRBTDP1APEX1KIF11KMT2A | |
| SCHEMBL5285126 | 0.84 | THRB (0.55) | THRBTDP1APEX1KIF11KMT2A | |
| SCHEMBL6187511 | 0.83 | THRB (0.50) | THRBTDP1APEX1PDK2MAPT | |
| SCHEMBL15691564 | 0.82 | THRB (0.57) | THRBTDP1APEX1KIF11KMT2A | |
| SCHEMBL1701331 | 0.80 | THRB (0.47) | THRBTDP1APEX1 | |
| SCHEMBL5863723 | 0.79 | THRB (0.46) | THRBTDP1APEX1PDK2 | |
| SCHEMBL6650659 | 0.79 | HDAC1 (0.46) | THRBTDP1APEX1GAAMAPT | |
| Hydrochloric Acid SCHEMBL6777668 | 0.78 | THRB (0.44) | THRBTDP1APEX1PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101838218-A | Ester compound and pharmaceutical use of the same | JAPAN TOBACCO INC | 2010-09-22 | — | — | CN | disclosed |
| US-20100158996-A1 | ESTER COMPOUND AND MEDICAL USE THEREOF | JAPAN TOBACCO INC. | 2010-06-24 | — | — | US | disclosed |
| CN-1630629-B | Ester compound and medical use thereof | JAPAN TOBACCO INC | 2010-05-05 | — | — | CN | disclosed |
| US-7625948-B2 | Ester compound and medicinal use thereof | JAPAN TOBACCO INC. (JP) | 2009-12-01 | — | — | US | disclosed |
| CN-1943786-A | Ester compound and its medicinal application | JAPAN TOBACCO INC (JP) | 2007-04-11 | — | — | CN | disclosed |
| CN-1630629-A | Ester compound and medical use thereof | JAPAN TOBACCO INC (JP) | 2005-06-22 | — | — | CN | disclosed |
| US-20050075367-A1 | Ester compound and medicinal use thereof | JAPAN TOBACCO INC. (JP) | 2005-04-07 | — | — | US | disclosed |
| EP-1479666-A1 | ESTER COMPOUND AND MEDICINAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2004-11-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050075367-A1 | Ester compound and medicinal use thereof | LIPC, CES1, MTTP | THRB 347/4885TDP1 1604/4885APEX1 2984/4885 |
| US-20100158996-A1 | ESTER COMPOUND AND MEDICAL USE THEREOF | LIPC, CES1, MTTP | THRB 460/4885TDP1 1985/4885APEX1 3655/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.