Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | PDE2A | O00408 | 2/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.38 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.35 |
| ▸ | PDE4A | P27815 | 3/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.34 |
| ▸ | ACACB | O00763 | 3/20 | 0.34 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 2/20 | 0.34 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.34 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26345001 | 0.81 | ACACB (0.40) | HRH3PDE2APDE10AALKLRRK2 | |
| SCHEMBL29416754 | 0.81 | ACACB (0.40) | HRH3PDE2APDE10AALKLRRK2 | |
| SCHEMBL26345034 | 0.81 | ACACB (0.40) | HRH3PDE2APDE10AALKLRRK2 | |
| SCHEMBL29416716 | 0.81 | ACACB (0.40) | HRH3PDE2APDE10AALKLRRK2 | |
| SCHEMBL28703678 | 0.81 | ACACB (0.40) | HRH3PDE2APDE10AALKLRRK2 | |
| SCHEMBL28376456 | 0.76 | ALDH1A1 (0.56) | HRH3ACACBSLC5A1SLC5A2 | |
| SCHEMBL20576262 | 0.76 | ALDH1A1 (0.56) | HRH3ACACBSLC5A1SLC5A2 | |
| SCHEMBL924708 | 0.76 | ALDH1A1 (0.56) | HRH3ACACBSLC5A1SLC5A2 | |
| SCHEMBL28376632 | 0.74 | SRC (0.42) | HRH3ACACBGRM5 | |
| SCHEMBL29588562 | 0.74 | SRC (0.42) | HRH3ACACBGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2242741-A1 | CYCLOALKOXY-SUBSTITUTED 4-PHENYL-3,5-DICYANOPYRIDINES AND USE THEREOF | Bayer Schering Pharma Aktiengesellschaft (DE) | 2010-10-27 | — | — | EP | disclosed |
| WO-2009100827-A1 | CYCLOALKOXY-SUBSTITUTED 4-PHENYL-3,5-DICYANOPYRIDINES AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-08-20 | — | — | WO | disclosed |