Sugi Predict

Sugi Predict / Compounds / SCHEMBL924708

SCHEMBL924708

SCHEMBL924708

O=Cc1ccc(OC2CCOC2)cc1

nearest known ligand 0.56

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 3/20 0.56
▸ KDM4E B2RXH2 1/20 0.56
▸ CYP2A6 P11509 1/20 0.40
▸ ACACB O00763 3/20 0.40
▸ HRH3 Q9Y5N1 2/20 0.39
▸ FAAH O00519 1/20 0.38
▸ EPHX2 P34913 1/20 0.38
▸ SLC5A2 P31639 4/20 0.37
▸ SLC5A1 P13866 3/20 0.37
▸ ALDH1A3 P47895 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28376456 1.00 ALDH1A1 (0.56) ALDH1A1KDM4ECYP2A6ACACBHRH3
SCHEMBL20576262 1.00 ALDH1A1 (0.56) ALDH1A1KDM4ECYP2A6ACACBHRH3
SCHEMBL22821050 0.95 ALDH1A1 (0.51) ALDH1A1KDM4ECYP2A6ACACBHRH3
SCHEMBL22820929 0.95 ALDH1A1 (0.51) ALDH1A1KDM4ECYP2A6ACACBHRH3
SCHEMBL22821099 0.95 ALDH1A1 (0.51) ALDH1A1KDM4ECYP2A6ACACBHRH3
SCHEMBL934830 0.90 ALDH1A1 (0.59) ALDH1A1KDM4ECYP2A6ACACBHRH3
SCHEMBL28376659 0.86 ALDH1A1 (0.58) ALDH1A1KDM4ECYP2A6ACACBFAAH
SCHEMBL28371609 0.81 SRC (0.42) ACACBHRH3
SCHEMBL29664363 0.81 SRC (0.42) ACACBHRH3
SCHEMBL29588562 0.81 SRC (0.42) ACACBHRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120058647-A Diphenyl methane derivative and its preparation method and application 中南大学 2025-05-30 — — CN claimed
CN-112641773-A Composition containing heterocyclic compound and use thereof 黄泳华 2021-04-13 — — CN claimed
CN-111265512-A Composition containing a mixture of benzyl benzene derivatives and uses thereof 黄泳华 2020-06-12 — — CN claimed
CN-120058647-A Diphenyl methane derivative and its preparation method and application 中南大学 2025-05-30 — — CN disclosed
WO-2025088634-A1 A PROCESS FOR THE PREPARATION OF GLIFLOZIN AGLYCONES COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2025-05-01 — — WO disclosed
CN-114539229-B Pyrimidine diketone derivative, preparation method and medical application thereof 江苏恒瑞医药股份有限公司 2024-10-22 — — CN disclosed
CN-117299223-A Synthetic method of intermediate for preparing enggliflozin 沧州那瑞化学科技有限公司 2023-12-29 — — CN disclosed
CN-115417836-B Method for synthesizing Liujing hypoglycemic intermediate by using continuous flow 安庆奇创药业有限公司 2023-05-19 — — CN disclosed
CN-115417836-A Method for synthesizing lean hypoglycemic drug intermediate by using continuous flow 安庆奇创药业有限公司 2022-12-02 — — CN disclosed
CN-114773373-A Preparation method of engagliflozin key intermediate and engagliflozin impurity 浙江普洛家园药业有限公司 2022-07-22 — — CN disclosed
CN-114539229-A Pyrimidinedione derivatives, preparation method and medical application thereof 江苏恒瑞医药股份有限公司 2022-05-27 — — CN disclosed
CN-111265512-A Composition containing a mixture of benzyl benzene derivatives and uses thereof 黄泳华 2020-06-12 — — CN disclosed
CN-110981876-A 8-substituted styrylxanthine derivatives and uses thereof 广东东阳光药业有限公司 2020-04-10 — — CN disclosed
US-20180346502-A1 Processes for the Preparation of SGLT-2 Inhibitors, Intermediates Thereof EMMENNAR PHARMA PRIVATE LIMITED (IN) 2018-12-06 — — US disclosed
US-20110021487-A1 CYCLOALKOXY-SUBSTITUTED 4-PHENYL-3,5-DICYANOPYRIDINES AND THEIR USE BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2011-01-27 — — US disclosed
US-20110021487-A1 CYCLOALKOXY-SUBSTITUTED 4-PHENYL-3,5-DICYANOPYRIDINES AND THEIR USE BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2011-01-27 — — US disclosed
US-20110021487-A1 CYCLOALKOXY-SUBSTITUTED 4-PHENYL-3,5-DICYANOPYRIDINES AND THEIR USE BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2011-01-27 — — US disclosed
EP-2242741-A1 CYCLOALKOXY-SUBSTITUTED 4-PHENYL-3,5-DICYANOPYRIDINES AND USE THEREOF Bayer Schering Pharma Aktiengesellschaft (DE) 2010-10-27 — — EP disclosed
WO-2009100827-A1 CYCLOALKOXY-SUBSTITUTED 4-PHENYL-3,5-DICYANOPYRIDINES AND USE THEREOF BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2009-08-20 — — WO disclosed
WO-2009100827-A1 CYCLOALKOXY-SUBSTITUTED 4-PHENYL-3,5-DICYANOPYRIDINES AND USE THEREOF BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2009-08-20 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110021487-A1 CYCLOALKOXY-SUBSTITUTED 4-PHENYL-3,5-DICYANOPYRIDINES AND THEIR USE PC, DPP4, FABP3 ALDH1A1 1899/4885KDM4E 1690/4885CYP2A6 587/4885
US-20180346502-A1 Processes for the Preparation of SGLT-2 Inhibitors, Intermediates Thereof SLC5A2, SLC5A1, SLC2A4 ALDH1A1 2049/4885KDM4E 1818/4885CYP2A6 512/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.